Results 71 to 80 of about 476,398 (246)

Shh production and Gli signaling is activated in vivo in lung, enhancing the Th2 response during a murine model of allergic asthma [PDF]

, 2017
The pathophysiology of allergic asthma is driven by T-helper 2 (Th2) immune responses following aeroallergen inhalation. The mechanisms that initiate, potentiate and regulate airways allergy are incompletely characterized.
Crompton, Tessa, Furmanski, Anna L., Ross, Rosie, Standing, Ariane S.I., Yánez, Diane C.   +4 more
core   +3 more sources

Nebulized heparin in burn patients with inhalation trauma : safety and feasibility [PDF]

, 2020
Background: Pulmonary hypercoagulopathy is intrinsic to inhalation trauma. Nebulized heparin could theoretically be beneficial in patients with inhalation injury, but current data are conflicting.
Binnekade, Jan M., Cleffken, Berry, Colpaert, Kirsten, Dixon, Barry, Glas, Gerie J., Hollmann, Markus W., Horn, Janneke, Juffermans, Nicole P., Knape, Paul, Levi, Marcel M., Loef, Bert G., Mackie, David P., Malbrain, Manu, Muller, Jan, Preckel, Benedikt, Reidinga, Auke C., Schultz, Marcus J., van der Sluijs, K.F.   +17 more
core   +2 more sources

Gourd‐Inspired Design of Unit Cell with Multiple Gradients for Physiological‐Range Pressure Sensing

Advanced Functional Materials, EarlyView.
Gourd‐shaped micro‐dome arrays with coordinated modulus, conductivity, and geometric gradients co‐optimize sensitivity and linearity in piezoresistive tactile sensors. Under pressure, a solid upper dome embeds into a porous lower dome, triggering rapid contact‐area growth and series‐to‐parallel conduction, enabling unsaturated, intensity‐resolved ...
Jiayi Xu, Ming Lei, Yuanzhe Liang, Biao Qi, Ziyi Dai, Yong Zhao, Bingpu Zhou   +6 more
wiley   +1 more source

Human lung epithelial cell A549 proteome data after treatment with titanium dioxide and carbon black

Data in Brief, 2016
Here, we have described the dataset relevant to the A549 cellular proteome changes after exposure to either titanium dioxide or carbon black particles as compared to the non-exposed controls, “Proteomic changes in human lung epithelial cells (A549) in ...
Ngoc Q. Vuong, Patrick Goegan, Susantha Mohottalage, Dalibor Breznan, Marianne Ariganello, Andrew Williams, Fred Elisma, Subramanian Karthikeyan, Renaud Vincent, Premkumari Kumarathasan   +9 more
doaj   +1 more source

Comparison of serious inhaler technique errors made by device-naïve patients using three different dry powder inhalers: a randomised, crossover, open-label study [PDF]

, 2016
Background: Serious inhaler technique errors can impair drug delivery to the lungs. This randomised, crossover, open-label study evaluated the proportion of patients making predefined serious errors with Pulmojet compared with Diskus and Turbohaler dry ...
A Palander, A Papi, Anne Burden, AS Melani, BL Laube, Catherine Hutton, D Price, D Price, D Price, D Price, David B. Price, Dawn Shan, E Mehuys, Erika Sims, F Lavorini, F Yildiz, Federico Lavorini, GK Crompton, GN Rootmensen, H Al-Jahdali, H Chrystyn, Henry Chrystyn, IA Basheti, J Haughney, J Haughney, J Palen van der, J Steier, JC McElnay, JC Virchow, JL Rau, John Efthimiou, John Haughney, KG Nielsen, L Borgstrom, M Molimard, M Molimard, M Moller, M Schulte, MA Crane, Mathieu Molimard, MS Blaiss, Nicolas Roche, PN Dekhuijzen, RA Al-Showair, S Verver, Sinthia Bosnic-Anticevich, SP Newman, SZ Bosnic-Anticevich, V Giraud, V Giraud, V Giraud, W Azouz, Y Aydemir   +52 more
core   +2 more sources

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Diesel Exhaust Activates & Primes Microglia: Air Pollution, Neuroinflammation, & Regulation of Dopaminergic Neurotoxicity [PDF]

, 2011
BACKGROUND: Air pollution is linked to central nervous system disease, but the mechanisms responsible are poorly understood. OBJECTIVES: Here, we sought to address the brain-region-specific effects of diesel exhaust (DE) and key cellular mechanisms ...
Block, Michelle L, Duke, Laura, Johnson, Jo Anne, Kodavanti, Prasada, Kodavanti, Urmila, Levesque, Shannon, Lull, Melinda E., Stadler, Krisztian, Surace, Michael J., Taetzsch, Thomas, Wagner, Alison   +10 more
core   +1 more source

Review of hypoxaemia in the anaesthetized horse: predisposing factors, consequences and management [PDF]

, 2017
Objectives: To discuss how hypoxaemia might be harmful and why the horse is particularly predisposed to developing it. To review the strategies that are used to manage hypoxaemia in anaesthetised horses, to describe how successful these strategies are
Auckburally, Adam, Nyman, Görel
core   +1 more source

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

Advanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian, Iris E. Allijn, Laura Veenendaal, Nicole Bassous, Su Ryon Shin, Jeroen Leijten   +5 more
wiley   +1 more source

Physical and geometric constraints explain the labyrinth-like shape of the nasal cavity

, 2017
The nasal cavity is a vital component of the respiratory system that heats and humidifies inhaled air in all vertebrates. Despite this common function, the shapes of nasal cavities vary widely across animals.
Brenner, Michael P., Lieberman, Daniel E., Ostilla-Mónico, Rodolfo, Zwicker, David   +3 more
core   +1 more source