Results 91 to 100 of about 583,633 (342)
Advanced Science, EarlyView.As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang +10 more
wiley +1 more source
Трансплантология (Москва), 2016 Objective: To determine the efficacy of epidural anesthesia as part of combination inhalation anesthesia in patients undergoing kidney and pancreas transplantationMaterial: The study enrolled 21 patients after combined kidney and pancreas transplantation
M. Sh. Khubutiya +5 more
doaj
Carbogen inhalation during Non-Convulsive Status Epilepticus: A quantitative analysis of EEG recordings [PDF]
arXiv, 2019 Objective: To quantify the effect of inhaled 5% carbon-dioxide/95% oxygen on EEG recordings from patients in non-convulsive status epilepticus (NCSE). Methods: Five children of mixed aetiology in NCSE were given high flow of inhaled carbogen (5% carbon dioxide/95% oxygen) using a face mask for maximum 120s. EEG was recorded concurrently in all patients.
arxiv
Quantification of depth of anesthesia by nonlinear time series analysis of brain electrical activity [PDF]
, 2000 We investigate several quantifiers of the electroencephalogram (EEG) signal with respect to their ability to indicate depth of anesthesia. For 17 patients anesthetized with Sevoflurane, three established measures (two spectral and one based on the bispectrum), as well as a phase space based nonlinear correlation index were computed from consecutive EEG
arxiv +1 more source
Advanced Science, EarlyView.Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li +12 more
wiley +1 more source
BioMed Research International, 2014 Background. The aim of this study is to compare the effects of sevoflurane and propofol on one lung ventilation (OLV) induced ischemia-reperfusion injury (IRI) by determining the blood gas, ischemia-modified albumin (IMA), and malonyldialdehyde (MDA ...
E. Erturk +7 more
semanticscholar +1 more source
Effects of Propofol on Electrocardiogram Measures in Mice
Journal of Pharmacological Sciences, 2014 .: We investigated the anesthetic effects of propofol on the electrocardiogram (ECG) in mice. We also compared the effects of isoflurane (2%) inhalation anesthesia, intraperitoneal propofol (50 or 100 mg/kg), and pentobarbital (50 mg/kg) on ECG in mice ...
Tomohiro Shintaku +10 more
doaj
USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
Вестник анестезиологии и реаниматологии, 2018 Protection of myocardium from ischemic and reperfusion lesions continues to be an important issue in the modern cardiac surgery. Russian and foreign publications contain a significant number of data about the protective impact of pre- and post ...
E. Yu. Chepurnyak +2 more
doaj +1 more source
An Adaptive Neuro-fuzzy Strategy in Closed-loop Control of Anesthesia [PDF]
arXiv, 2019 This paper proposes an adaptive neuro-fuzzy framework to improve drug infusion rate in closed-loop control of anesthesia. The proposed controller provides a sub-optimal propofol administration rate as input to reach the desired bispectral index, which is the output of the system, in both induction and maintenance phases.
arxiv
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Advanced Science, EarlyView.The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari +20 more
wiley +1 more source