eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation
Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha +6 more
wiley +1 more source
This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman +6 more
wiley +1 more source
Nitrous oxide inhalation combined with lidocaine local anesthesia on the comfort of plastic surgery outpatient procedures: a randomized, controlled, single-blind trial. [PDF]
Su Y +7 more
europepmc +1 more source
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad +11 more
wiley +1 more source
The effect of intravenous anesthesia on postoperative cognitive function in patients undergoing painless gastroscopy: a meta-analysis. [PDF]
Jia Z +5 more
europepmc +1 more source
Effect of Intravenous, Inhalational, or Combined Anesthesia Maintenance on Postoperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy (AmPRAEC): A Multicenter Randomized Clinical Trial. [PDF]
Shen F +16 more
europepmc +1 more source
Pediatric Anesthesia, Psychology, and Interventions: A Narrative Review. [PDF]
Yu Q, Han Q, Yan R, Ding X.
europepmc +1 more source
Influence of sevoflurane combined with propofol anesthesia on the anesthesia effect and adverse reactions in children with acute appendicitis. [PDF]
Zhang P, Zhang J, Chen F.
europepmc +1 more source
National trends in dental sedation and general anesthesia in Japan before and during the COVID-19 pandemic: a descriptive epidemiological study using National Database Open Data Japan. [PDF]
Nitta Y +6 more
europepmc +1 more source

