Results 231 to 240 of about 583,633 (342)

Beta2‐adrenergic agonist salbutamol exhibits enantioselective disposition in skeletal muscle of lean young men following oral administration

open access: yesDrug Testing and Analysis, EarlyView.
Oral administration of salbutamol shows enantioselective disposition in human skeletal muscle, favoring the (S)‐enantiomer with higher relative partitioning of the pharmacologically active (R)‐enantiomer in muscle. This is concerning from an anti‐doping point of view because the anabolic properties demonstrated for salbutamol can potentially be ...
Morten Hostrup   +5 more
wiley   +1 more source

Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model

open access: yesDrug Testing and Analysis, EarlyView.
The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand   +4 more
wiley   +1 more source

Evaluation of Gastric pH and Gastrin Concentrations in Horses Subjected to General Inhalation Anesthesia in Dorsal Recumbency. [PDF]

open access: yesAnimals (Basel)
Guerrero JLS   +8 more
europepmc   +1 more source

Wavelet and pain rating index for inhalation anesthesia: A randomized controlled trial. [PDF]

open access: yesWorld J Clin Cases, 2020
Zhang JW   +4 more
europepmc   +1 more source

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy. We now address the question of whether inhibition of calpain function in cardiomyocytes, and thereby ...
Gregor Sachse   +9 more
wiley   +1 more source

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