Results 81 to 90 of about 44,727 (264)

A new inhalation anesthesia method

open access: yesAsian Journal of Surgery, 2023
Chao Gao, Yuan Sun, Xiao Huang
openaire   +3 more sources

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang   +15 more
wiley   +1 more source

Regulating the Interaction Between Near‐Infrared Dye and Endogenous Albumin for Concurrent Imaging Skin Inflammation and Neovascularization After Flap Transplantation

open access: yesAggregate, EarlyView.
This study identified a near‐infrared (NIR) dye with superior covalent albumin‐binding capability, enabling high‐contrast imaging of skin inflammation with minimal background interference. This work further demonstrated dual‐channel imaging of skin barrier disruption and neovascularization in flap transplantation models, and allowed simultaneous ...
Yijing Du   +5 more
wiley   +1 more source

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