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Association between genotoxic properties of inhalation anesthetics and oxidative stress biomarkers
Toxicology and industrial health, 2020Exposure to inhalation anesthetics (IAs) has been associated with DNA damage as reflected in the increased frequency of micronuclei (MN) and chromosomal aberrations (CAs).
M. Neghab +5 more
semanticscholar +1 more source
Fluorine-Containing Inhalation Anesthetics: Chemistry, Properties, and Pharmacologies.
Current Medicinal Chemistry, 2019The stories of fluorinated inhalation anesthetics, including synthesis, physicochemistry and pharmacologies, were summarized in this review. Retrospecting the history of inhalation anesthetics revealed their increasing reliance on fluorine and ether ...
Yuzhong Wang +2 more
semanticscholar +1 more source
Der Anaesthesist, 2014
Inhaled anesthetics are inhaled via the lungs. They subsequently pass through the alveolocapillary membrane and diffuse into the blood to finally target the central nervous system and induce anesthesia. This principle of anesthesia induction was first described for diethylether in 1847.
M, Deile, M, Damm, A R, Heller
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Inhaled anesthetics are inhaled via the lungs. They subsequently pass through the alveolocapillary membrane and diffuse into the blood to finally target the central nervous system and induce anesthesia. This principle of anesthesia induction was first described for diethylether in 1847.
M, Deile, M, Damm, A R, Heller
openaire +3 more sources
Anesthesiology, 1994
Desflurane and sevoflurane provide one clear advantage over other currently available potent inhaled anesthetics. Their lower solubilities permit a more precise control over the delivery of anesthesia and a more rapid recovery from anesthesia. Most of their other properties reflect similar properties of their predecessors--with a few exceptions. Indeed,
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Desflurane and sevoflurane provide one clear advantage over other currently available potent inhaled anesthetics. Their lower solubilities permit a more precise control over the delivery of anesthesia and a more rapid recovery from anesthesia. Most of their other properties reflect similar properties of their predecessors--with a few exceptions. Indeed,
openaire +2 more sources
American Journal of Health-System Pharmacy, 2006
The pharmacology, bioavailability and pharmacokinetics, indications, clinical efficacy, adverse effects and toxicities, and dosage and administration of the inhaled anesthetics are reviewed.The inhaled anesthetics include desflurane, enflurane, halothane, isoflurane, and sevoflurane and are thought to enhance inhibitory postsynaptic channel activity ...
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The pharmacology, bioavailability and pharmacokinetics, indications, clinical efficacy, adverse effects and toxicities, and dosage and administration of the inhaled anesthetics are reviewed.The inhaled anesthetics include desflurane, enflurane, halothane, isoflurane, and sevoflurane and are thought to enhance inhibitory postsynaptic channel activity ...
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Der Anaesthesist, 2021
Inhalational anesthetics have been used for induction and maintenance of general anesthesia for more than 150 years. All of the currently used inhalational anesthetics are chlorinated and fluorinated derivatives of ether. Dosing is carried out using the minimal alveolar concentration (MAC) concept.
Jan, Jedlicka +5 more
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Inhalational anesthetics have been used for induction and maintenance of general anesthesia for more than 150 years. All of the currently used inhalational anesthetics are chlorinated and fluorinated derivatives of ether. Dosing is carried out using the minimal alveolar concentration (MAC) concept.
Jan, Jedlicka +5 more
openaire +1 more source
Fluorinated Inhalation Anesthetics
, 1994No class of chemical compounds has contributed more toward the elimination of hospital trauma than anesthetics. These drugs have changed the operating room from a chamber of horrors to a place where medical care is provided in a tranquil atmosphere to some 50 million patients every year.
D. Halpern
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