Results 61 to 70 of about 40,592 (266)

Inhaled Corticosteroid Therapy Does Not Control Asthma

Canadian Respiratory Journal, 2004
BACKGROUND: Randomized clinical trials demonstrate efficacy and show that inhaled corticosteroid therapy can control asthma, but details concerning their effectiveness in achieving this goal in the community are lacking.
Robert L Cowie, Margot F Underwood, Stephen K Field   +2 more
doaj   +1 more source

Superior Labial Artery Flap for Septal Perforation Repair: The Boxer's Flap

The Laryngoscope, EarlyView.
The nasal floor flap, or Boxer's flap, is an anteriorly pedicled, superior labial artery–based mucosal flap that provides excellent closure rates in septal perforation repair when traditional septal flaps are not feasible. The schematic shows: (A) preoperative perforation, (B) nasal floor flap elevation (with the pedicle maintained at the inferior ...
Nicholas J. Campion, Zhanna Mokoyan, Viktoriya Stepanova, Isam Alobid, Richard J. Harvey, Yury Rusetsky   +5 more
wiley   +1 more source

A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial

Trials, 2018
Background Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease.
Catherine E. Hanratty, John G. Matthews, Joseph R. Arron, David F. Choy, Ian D. Pavord, P. Bradding, Christopher E. Brightling, Rekha Chaudhuri, Douglas C. Cowan, Ratko Djukanovic, Nicola Gallagher, Stephen J. Fowler, Tim C. Hardman, Tim Harrison, Cécile T. Holweg, Peter H. Howarth, James Lordan, Adel H. Mansur, Andrew Menzies-Gow, Sofia Mosesova, Robert M. Niven, Douglas S. Robinson, Dominick E. Shaw, Samantha Walker, Ashley Woodcock, Liam G. Heaney, on behalf of the RASP-UK (Refractory Asthma Stratification Programme) Consortium   +26 more
doaj   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

The Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen, Carmen Esna, Camille Prigent, Anna Miles   +3 more
wiley   +1 more source

Bilateral Patellar Tendon Rupture in a 64-Year-Old Man: Possible Interaction of Inhaled Corticosteroids, Age and Mechanical Stress

Case Reports in Orthopedics
Bilateral rupture of the patellar tendon is a rare occurrence, most often associated with systemic disease or exposure to systemic corticosteroids or fluoroquinolones.
Mohamed Jalaleddin, Pavun Basra, Christopher Jordan, Benjamin H. L. Harris, Louis J. Koizia   +4 more
doaj   +1 more source

Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review

The Laryngoscope, EarlyView.
Nasal septal perforation (NSP) repair using the anterior ethmoidal artery (AEA) flap is an emerging endoscopic technique with an overall closure success rate of 84.6%. The AEA flap is a reliable endoscopic technique for repairing NSPs < 2.5 cm. Emerging AEA flap modifications may further improve outcomes, while enabling repair of larger perforations ...
Hemali P. Shah, Ethan Tsao, Alhan Sayyed, C. Scott Dorris, John R. Craig, Daniel B. Spielman   +5 more
wiley   +1 more source

Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients

Canadian Respiratory Journal, 2006
BACKGROUND: Inhaled corticosteroids are powerful drugs that can suppress airway inflammation in asthmatic patients. Deposition of most of the inhaled corticosteroid occurs mainly in the central airways.
Hans-Peter Hauber, Rame Taha, Celine Bergeron, Vladimir Migounov, Qutayba Hamid, Ron Olivenstein   +5 more
doaj   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Patient response and remission in respiratory disease: Special focus on severe asthma and chronic obstructive pulmonary disease

Journal of International Medical Research
Over the past decades, monoclonal antibodies have been playing a pivotal role in the treatment of chronic inflammatory airway diseases. Currently, ample data are available on the efficacy and safety of biologics in asthma from randomized controlled ...
Stefania Colantuono, Francesco Menzella, Pier-Valerio Mari, Francesco Macagno, Francesco Lombardi, Ilaria Baglivo, Cristiano Caruso   +6 more
doaj   +1 more source

Montelukast: More than a Cysteinyl Leukotriene Receptor Antagonist?

The Scientific World Journal, 2010
The prototype cysteinyl leukotriene receptor antagonist, montelukast, is generally considered to have a niche application in the therapy of exercise- and aspirin-induced asthma.
Gregory R. Tintinger, Charles Feldman, Annette J. Theron, Ronald Anderson   +3 more
doaj   +1 more source