COPD: Optimizing Treatment [PDF]
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila +2 more
core +1 more source
Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. [PDF]
BackgroundGlobal gene expression levels are known to be highly dependent upon gross demographic features including age, yet identification of age-related genomic indicators has yet to be comprehensively undertaken in a disease and treatment-specific ...
Burchard, Esteban G +22 more
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Physician-prescribed Asthma Treatment Regimen does not differ Between Smoking and Non-smoking Patients With Asthma in Seoul and Gyunggi province of Korea [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any ...
Chalmers +27 more
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ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley +1 more source
BackgroundThere is much debate surrounding the use of inhaled bronchodilators and corticosteroids for infants with bronchopulmonary dysplasia (BPD).ObjectiveThe objective of this systematic review was to identify strengths and knowledge gaps in the ...
Brian J Clouse +2 more
doaj +1 more source
Once-daily use of inhaled corticosteroids: A new regimen in the treatment of persistent asthma
Asthma is a disease of chronic airway inflammation that is characterized clinically by bronchial hyper-responsiveness and airflow limitation. Chronic inflammation, coupled with ongoing repair of airways damaged by the persistent inflammatory process in ...
Jeffrey Leflein
doaj +1 more source
Integrating evidence for managing asthma in patients who smoke [PDF]
Peer reviewedPublisher ...
Bjermer, Leif +3 more
core +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Patient-physician discordance in assessment of adherence to inhaled controller medication: a cross-sectional analysis of two cohorts [PDF]
We aimed to compare patient's and physician's ratings of inhaled medication adherence and to identify predictors of patient-physician discordance.(SFRH/BPD/115169/2016) funded by Fundação para a Ciência e Tecnologia (FCT); ERDF (European Regional ...
Afonso, Ivete +68 more
core +3 more sources
Four patients with a history of acute exacerbations of COPD: implementing the CHEST/Canadian Thoracic Society guidelines for preventing exacerbations [PDF]
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if ...
A Singanayagam +43 more
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