Results 121 to 130 of about 48,911 (308)

Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD

, 2016
Yasuhiro Yamauchi,1 Hideo Yasunaga,2 Wakae Hasegawa,1 Yukiyo Sakamoto,1 Hideyuki Takeshima,1 Taisuke Jo,1,3 Hiroki Matsui,2 Kiyohide Fushimi,4 Takahide Nagase1 1Department of Respiratory Medicine, Graduate School of Medicine, 2Department of Clinical ...
Sakamoto Y, Hasegawa W, Fushimi K, Nagase T, Takeshima H, Yamauchi Y, Jo T, Matsui H, Yasunaga H   +8 more
core  

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

Allergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson, Maciej Kupczyk, Barbro Dahlén, Kenji Izuhara, Mina Gaga, Nikos M. Siafakas, Alberto Papi, Bianca Beghe, Guy Joos, Klaus F. Rabe, Elisabeth H. Bel, Sebastian L. Johnston, Pascal Chanez, Mark Gjomarkaj, Peter H. Howarth, Ewa Niżankowska‐Mogilnicka, Roelinde Middelveld, Sven‐Erik Dahlén, Apostolos Bossios, Anna James, on behalf of the BIOAIR (Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease) and ChAMP consortia   +20 more
wiley   +1 more source

Urinary Pharmacokinetic Methodology to Determine the Relative Lung Bioavailability of Inhaled Beclometasone

Urinary pharmacokinetic methods have been introduced to identify the relative lung and systemic availability of inhaled drugs but have not been extended to corticosteroids.
Said, Amira
core  

The dose of inhaled corticosteroids in patients with COPD: when less is better

, 2018
José Luis Izquierdo,1 Borja G Cosio2,3 1Department of Pneumology and Medicine, Hospital Universitario, Universidad de Alcalá, Guadalajara, Spain; 2Department of Respiratory Medicine, Hospital Son Espases-IdISBa, Palma de Mallorca, Spain ...
Izquierdo JL, Cosio BG
core  

An integrative review of systematic reviews related to the management of breathlessness in respiratory illnesses

, 2010
Background: breathlessness is a debilitating and distressing symptom in a wide variety of diseases and still a difficult symptom to manage. An integrative review of systematic reviews of non-pharmacological and pharmacological interventions for ...
Chris D Bailey, Rasha Dabbour, Dabbour Rasha, Bailey Chris D, Ann Caress, Bailey, Chris D., Richard Wagland, Smith, Jaclyn, Smith, Jaclyn; id_orcid, Alex Molassiotis, Wagland, Richard, Bailey, Chris, Caress Ann, Molassiotis, Alex, Wagland Richard, Caress, Ann, Molassiotis Alex, Dabbour, Rasha, Smith Jaclyn, Jaclyn Smith   +19 more
core   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Communication during counseling sessions about inhaled corticosteroids at the community pharmacy

, 2016
Jeanine A Driesenaar,1 Peter AGM De Smet,2,3 Rolf van Hulten,4,5 Litje Hu,1 Sandra van Dulmen1,6,7 1NIVEL, Netherlands institute for health services research, Utrecht, the Netherlands; 2Department of Clinical Pharmacy, Radboud University Medical Center,
van Dulmen S, Driesenaar JA, De Smet PAGM, Hu L, van Hulten R   +4 more
core  

Use of inhaled corticosteroids and risk of fractures

, 2000
Treatment with systemic corticosteroids is known to increase the risk of fractures but little is known of the fracture risks associated with inhaled corticosteroids.
Van Staa, Tjeerd; id_orcid, Leufkens, HG, Cooper, C., van Staa, T P, Universiteit Utrecht, Leufkens, H G, Leufkens, H.G.M., Cooper, Cyrus, Cooper, C, Dep Farmaceutische wetenschappen, Population-based studies of drug treatment: from molecule to patient outcomes, Van Staa, T.P., Van Staa, TP, Leufkens, H   +13 more
core   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

Intraclass Difference in Pneumonia Risk with Fluticasone and Budesonide in COPD: A Systematic Review of Evidence from Direct-Comparison Studies

International Journal of COPD, 2020
Thomas P Lodise,1 Jingyi Li,2 Hitesh N Gandhi,3 Gerald O’Brien,3 Sanjay Sethi4 1Department of Pharmacy Practice, Albany College Pharmacy and Health Sciences, Albany, NY, USA; 2Global Medical Affairs, AstraZeneca, Gaithersburg, MD, USA; 3US ...
Lodise TP, Li J, Gandhi HN, O’Brien G, Sethi S   +4 more
doaj