Results 171 to 180 of about 72,253 (289)

<i>SUMF1</i> Common Variant rs793391 Is Associated with Response to Inhaled Corticosteroids in Patients with COPD. [PDF]

open access: yesInt J Mol Sci
Ntenti C   +9 more
europepmc   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq   +2 more
wiley   +1 more source

Effect of Anthocyanin‐Rich New Zealand Blackcurrant on Tumour Necrosis Factor‐α–Induced Plasminogen Activator Inhibitor‐1 Release in Airway Epithelial Cells: A Preliminary Study

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Pretreatment with New Zealand blackcurrant anthocyanins nonsignificantly reduced TNF‐α–induced PAI‐1 release in bronchial epithelial cells. The small sample size may have influenced the lack of statistical significance. This study provides preliminary evidence of possible effects of NZBC anthocyanins on PAI‐1 secretion but warrants further extensive ...
Madiha Ajaz   +5 more
wiley   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy   +11 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche   +8 more
wiley   +1 more source

Beyond the Wheeze: Incidental Diagnosis of Eosinophilic Oesophagitis in a Young Child With Asthma‐Like Symptoms

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Sameena Tabassum   +3 more
wiley   +1 more source

ACTH Stimulation Testing Is Often Unnecessary After Appropriate Patient Preparation Prior to Screening Cortisol Measurement

open access: yesClinical Endocrinology, Volume 104, Issue 6, Page 567-573, June 2026.
ABSTRACT Context Screening morning serum cortisol is used to select patients for ACTH stimulation testing to diagnose adrenal insufficiency (AI) but may be affected by pre‐analytical factors. Careful consideration to discontinue confounding medications beforehand may preclude the need for subsequent stimulation testing.
Christopher J. Symonds   +2 more
wiley   +1 more source

Impact of nasal and inhaled corticosteroids on SARS-CoV-2 infection susceptibility. [PDF]

open access: yesJ Allergy Clin Immunol
Rosas-Salazar C   +31 more
europepmc   +1 more source

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