Results 41 to 50 of about 48,911 (308)

The use of inhaled corticosteroids in wheezy pre-school age children : current practice and literature review [PDF]

, 2007
Preschool children and infants frequently suffer wheezy episodes, mostly associated with viral respiratory tract infections. There is no evidence to support the use of maintenance low dose inhaled corticosteroids to prevent or manage episodic mild wheeze
Vella, Cecil
core  

Effects of short-term treatment with atorvastatin in smokers with asthma - a randomized controlled trial [PDF]

, 2011
<b>Background</b> The immune modulating properties of statins may benefit smokers with asthma. We tested the hypothesis that short-term treatment with atorvastatin improves lung function or indices of asthma control in smokers with asthma.<
Chaudhuri, Rekha, Lloyd, Suzanne M., Spears, Mark, Thomson, Neil C., Iona Donnelly, Lloyd, Suzanne M, Jolly, Lisa, Mair, Frances, Braganza Georgina, Mair Frances, Weir Christopher J, Frances Mair, Mark Spears, McSharry, Charles, Lafferty Jane, Christopher J Weir, Lloyd Suzanne M, McSharry Charles, Lisa Jolly, Braganza, Georgina, Weir, Christopher J., Spears, Mark; id_orcid, Lafferty, Jane, Rekha Chaudhuri, Charles McSharry, Thomson Neil C, Georgina Braganza, Thomson, Neil C, Chaudhuri Rekha, Neil C Thomson, Jane Lafferty, Suzanne M Lloyd, Spears Mark, Donnelly, Iona, Weir, Christopher J; id_orcid, Donnelly Iona, Jolly Lisa   +36 more
core   +1 more source

Use of inhaled corticosteroids in children [PDF]

Archives of Disease in Childhood, 2003
I read with interest the article Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom by Todd et al and the accompanying editorial in the December issue of Archives . In the reported cases, the children had been administered substantially (up to 5 times) higher than the Glaxo SmithKline (GSK) Core Data Sheet ...
openaire   +2 more sources

Effects of inhaled corticosteroids on bone [PDF]

The Netherlands Journal of Medicine, 1997
Inhaled corticosteroids (ICS) are the most effective therapy for asthma currently available. The increasing use of ICS raises the issue of possible adverse systemic effects. Since one of the most important side-effects of oral corticosteroids (OCS) is osteoporosis, this article focuses on current knowledge of the effects of ICS on bone.
Bootsma, G.P., Dekhuijzen, P.N.R., Festen, J., Herwaarden, C.L.A. van   +3 more
openaire   +4 more sources

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

Lower leukotriene C4 levels in bronchoalveolar lavage fluid of asthmatic subjects after 2.5 years of inhaled corticosteroid therapy

Mediators of Inflammation, 1995
Long-term treatment with inhaled corticosteroids has been shown to result in improvement of symptoms and lung function in subjects with asthma. Arachidonic acid (AA) metabolites are thought to play a role in the pathophysiology of asthma. It was assessed
Y. Oosterhoff, S. E. Overbeek, R. Douma, J. A. Noordhoek, D. S. Postma, H. C. Hoogsteden, F. J. Zijlstra   +6 more
doaj   +1 more source

Inhaled Corticosteroids in Lung Diseases [PDF]

American Journal of Respiratory and Critical Care Medicine, 2013
Abstract Inhaled corticosteroids (ICSs) are used extensively in the treatment of asthma and chronic obstructive pulmonary disease (COPD) due to their broad antiinflammatory effects. They improve lung function, symptoms, and quality of life and reduce exacerbations in both conditions but do not alter the progression of disease.
Hengameh H, Raissy, H William, Kelly, Michelle, Harkins, Stanley J, Szefler   +3 more
openaire   +2 more sources

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Effect of Budesonide Nasal Irrigation in Patients With Chronic Rhinosinusitis With Nasal Polyps Without Prior Sinus Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana, Isabela Pontes, Caio Floriano, Renato Rios, Marlos Cortez, Marcel Miyake   +5 more
wiley   +1 more source

Centrilobular Opacities in the Asthmatic Lung Successfully Treated with Inhaled Ciclesonide and Tiotropium: With Assessment of Alveolar Nitric Oxide Levels

Allergology International, 2011
Background: Despite the fact that bronchioles are involved in asthma, there have been limited asthmatic cases showing marked centrilobular opacities on computed tomography (CT) chest scans.
Hirofumi Kiyokawa, Hisako Matsumoto, Hitoshi Nakaji, Akio Niimi, Isao Ito, Kikuko Ono, Tomoshi Takeda, Tsuyoshia Oguma, Kojiro Otsuka, Michiaki Mishima   +9 more
doaj   +1 more source