Results 51 to 60 of about 41,522 (262)

Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology

Allergology International, 2002
The mainstay of chronic asthma management consists of using pharmacological agents that induce bronchodilatation, such as short-acting β-adrenergic receptor agonists (bronchodilators or relievers), and that control the chronic inflammatory process, such ...
Kian Fan Chung
doaj   +1 more source

Evidence for the Management of Bronchopulmonary Dysplasia in Very Preterm Infants

Children, 2021
Background: Very preterm birth often results in the development of bronchopulmonary dysplasia (BPD) with an inverse correlation of gestational age and birthweight.
Tobias Muehlbacher, Dirk Bassler, Manuel B. Bryant   +2 more
doaj   +1 more source

Twenty years of inhaler therapy: A nationwide drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to map nationwide trends and prescribing patterns in inhaler use from 2004 to 2023. In light of evolving clinical guidelines and attention to the environmental impact of inhalers within recent years, we also examined variation in prescribing behaviour and patient‐level treatment choices. Methods Using nationwide health registries,
Katrine Bitsch Johansen, Lars Christian Lund, Zandra Nymand Ennis, Andrew Scourfield, Anders Løkke, Sidsel Arnspang Pedersen   +5 more
wiley   +1 more source

Corticóide inalatório: efeitos no crescimento e na supressão adrenal Inhaled corticosteroids: effects on growth and adrenal suppression

Jornal Brasileiro de Pneumologia, 2005
Este artigo é uma revisão da literatura médica sobre os corticosteróides inalatórios e seus efeitos no crescimento e na supressão adrenal em crianças e adolescentes.
Elisete E. Arend, Gilberto Bueno Fischer, Helena Mocelin, Lídia Medeiros   +3 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis

BMC Medicine, 2009
Background Most patients with chronic obstructive pulmonary disease (COPD) receive inhaled long-acting bronchodilators and inhaled corticosteroids. Conventional meta-analyses established that these drugs reduce COPD exacerbations when separately compared
ter Riet Gerben, Kleijnen Jos, Bachmann Lucas M, Puhan Milo A, Kessels Alphons G   +4 more
doaj   +1 more source

Pneumocoele sinus: Computed tomographic findings and surgical approach in a 2‐year‐old Cob filly

Equine Veterinary Journal, EarlyView.
Abstract Background Pneumosinus dilatans and pneumocoele sinus describe abnormal hyperpneumatisation of paranasal sinuses, with the latter being accompanied by thinning of bony walls. Although recognised in human and equine medicine, to the authors' knowledge, this condition's computed tomography (CT) findings and successful surgical approach in horses
Sarah L. Thompson, Manon W. J. Peeters, Gabriel Manso‐Díaz, Andrew R. Fiske‐Jackson   +3 more
wiley   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Inhaled versus systemic corticosteroids for acute exacerbations of COPD: a systematic review and meta-analysis

European Respiratory Review
This meta-analysis compares the efficacy and safety of inhaled versus systemic corticosteroids for COPD exacerbations. Following a pre-registered protocol, we appraised eligible randomised controlled trials (RCTs) according to Cochrane methodology ...
Efthymia Papadopoulou, Sulaiman Bin Safar, Ali Khalil, Jan Hansel, Ran Wang, Alexandru Corlateanu, Konstantinos Kostikas, Stavros Tryfon, Jørgen Vestbo, Alexander G. Mathioudakis   +9 more
doaj   +1 more source