Results 71 to 80 of about 41,522 (262)

Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review

The Laryngoscope, EarlyView.
Nasal septal perforation (NSP) repair using the anterior ethmoidal artery (AEA) flap is an emerging endoscopic technique with an overall closure success rate of 84.6%. The AEA flap is a reliable endoscopic technique for repairing NSPs < 2.5 cm. Emerging AEA flap modifications may further improve outcomes, while enabling repair of larger perforations ...
Hemali P. Shah, Ethan Tsao, Alhan Sayyed, C. Scott Dorris, John R. Craig, Daniel B. Spielman   +5 more
wiley   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

The Effect of Glucocorticoids on Bone Mass in Patients with Asthma and Chronic obstructive Pulmonary Disease

Türk Osteoporoz Dergisi, 2005
Inhaled corticosteroids and bronchodilators have become a key element in the maintenance treatment of bronchial asthma and chronic obstructive pulmanory disease (COPD).
Evrim Karadağ Saygı, Demet Ofluoğlu, Feyza Ünlü Özkan, Sait Karakurt   +3 more
doaj  

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source

The effects of inhaled and oral corticosteroids on serum inflammatory biomarkers in COPD: an exploratory study

Therapeutic Advances in Respiratory Disease, 2009
Background: Several studies suggest that inhaled and oral corticosteroids repress systemic inflammation in chronic obstructive pulmonary disease (COPD). However, the cytokines that may respond to these medications are unclear.
S.F. Paul Man, Xuekui Zhang, Rupert Vessey, Terry Walker, Kwan Lee, Dan Park, Don D. Sin   +6 more
doaj   +1 more source

Can inhaled fluticasone alone or in combination with salmeterol reduce systemic inflammation in chronic obstructive pulmonary disease? – study protocol for a randomized controlled trial [NCT00120978]

BMC Pulmonary Medicine, 2006
Background Systemic inflammation is associated with various complications in chronic obstructive pulmonary disease including weight loss, cachexia, osteoporosis, cancer and cardiovascular diseases.
Ramesh Warren, Mainra Rajesh R, York Ernest, Wong Eric, FitzGerald Mark, Ford Gordon, Marciniuk Darcy D, Man SF Paul, Sin Don D, Melenka Lyle S, Wilde Eric, Cowie Robert L, Williams Dave, Rousseau Roxanne   +13 more
doaj   +1 more source

Systematic Review of Inhaled Bronchodilator and Corticosteroid Therapies in Infants with Bronchopulmonary Dysplasia: Implications and Future Directions.

PLoS ONE, 2016
BackgroundThere is much debate surrounding the use of inhaled bronchodilators and corticosteroids for infants with bronchopulmonary dysplasia (BPD).ObjectiveThe objective of this systematic review was to identify strengths and knowledge gaps in the ...
Brian J Clouse, Sudarshan R Jadcherla, Jonathan L Slaughter   +2 more
doaj   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Once-daily use of inhaled corticosteroids: A new regimen in the treatment of persistent asthma

Allergology International, 2000
Asthma is a disease of chronic airway inflammation that is characterized clinically by bronchial hyper-responsiveness and airflow limitation. Chronic inflammation, coupled with ongoing repair of airways damaged by the persistent inflammatory process in ...
Jeffrey Leflein
doaj   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source