Results 51 to 60 of about 263,304 (259)

Potential Explosion Risk Comparison between SMR and DMR Liquefaction Processes at Conceptual Design Stage of FLNG

한국해양공학회지, 2018
An FLNG (floating liquefied natural gas) or LNG FPSO (floating production, storage and offloading) unit is a notable offshore unit with the increasing demand for LNG.
Wonwo You, Minho Chae, Jaeuk Park, Youngsub Lim   +3 more
doaj   +1 more source

Reaction Path Synthesis Based on Fuzzy Evaluation in Safety, Environment and Health Impact

Chemical Engineering Transactions, 2020
To eliminate hazards during early phase of chemical process and obtain chemical reaction path with benign safety, the strategy is proposed by considering safety factors during reaction path synthesis.
Xiaoyan Sun, Yao Fang, Wei Jiao, Shuguang Xiang   +3 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Inherent Safety Assessment for Two Solar-based Fuels Production Processes: Methanol via CO2 Catalytic Hydrogenation and Biodiesel from Microalgal Oil

Chemical Engineering Transactions, 2020
Safety is an aspect of primary relevance in early-process design and can hardly be neglected: the consequences of accidents in chemical plants have always high impact on economics and reputation.
Mariasole Cipolletta, Valeria Casson Moreno, Valerio Cozzani   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Experimental Parameter Study and Inherent Scattering of Safety Characteristics of Dusts

Chemical Engineering Transactions, 2023
Safety characteristics are widely used in industrial processes to avoid explosive atmospheres (primary explosion protection) or to mitigate the consequences of an explosion (constructive explosion protection).
Stefan H. Spitzer, Arne Krietsch, Vojtech Jankuj   +2 more
doaj  

Inherent Safety Assessment of Industrial-Scale Production of Chitosan Microbeads Modified with TiO₂ Nanoparticles. [PDF]

Biomolecules, 2021
Meramo-Hurtado S, Ceballos-Arrieta N, Cortes-Caballero J, Leon-Pulido J, Gonzalez-Quiroga A, Gonzalez-Delgado ÁD.   +5 more
europepmc   +1 more source