Results 61 to 70 of about 240,946 (255)
Using Principles of Inherent Safety for Design of Hydrometallurgical Solvent Extraction Plants
Chemical Engineering Transactions, 2013 An Inherently Safe (IS) facility relies on the reduction or elimination of hazardous materials or processes through changes in the chemistry, physics and physical design of a process rather than by relying entirely on layers of add-on protection.
L. Moore
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Value Conflicts in Designing for Safety: Distinguishing Applications of Safe-by-Design and the Inherent Safety Principles. [PDF]
Int J Environ Res Public Health, 2021 Bouchaut B +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Nuclear Engineering and Technology, 2016 The Prototype Gen IV sodium cooled fast reactor (PGSFR) has been developed for the last 4 years, fulfilling the technology demonstration of the burning capability of transuranic elements included in light water reactor spent nuclear fuel.
Jaewoon Yoo +7 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
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Neutronic characteristic analysis of the GAMA microreactor
HeliyonThe GAMA Microreactor is a low-power nuclear power plant dedicated for remote area with a power output of 300 kWe. The primary characteristics of the GAMA Microreactor are its system compactness, design simplicity, and safe operation without moving parts.
Andang Widi Harto +7 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
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Chemical Engineering Transactions, 2014 Organizations associated with the handling, processing or storage of hazardous substances, have the potential for major accidents. The offshore industry, for example, handles dangerous substances like crude oil and gas.
P. Okoh, S. Haugen
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Inherent Safety in Offshore Drilling Operations
International Journal of Recent Technology and Engineering (IJRTE), 2019 Inherent safety (IS) is a proactive approach for safety management during process plant design and operation. It has been proven that, considering the lifetime costs of a process and its operation, an inherently safer approach is an environmentally friendly and cost-optimal option. IS can be incorporated at any stage of design and operation.
Siti Rafidah Ab Rashid* +1 more
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