Results 81 to 90 of about 1,035,048 (296)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Overall System Description and Safety Characteristics of Prototype Gen IV Sodium Cooled Fast Reactor in Korea

open access: yesNuclear Engineering and Technology, 2016
The Prototype Gen IV sodium cooled fast reactor (PGSFR) has been developed for the last 4 years, fulfilling the technology demonstration of the burning capability of transuranic elements included in light water reactor spent nuclear fuel.
Jaewoon Yoo   +7 more
doaj   +1 more source

Inherent Safety Assessment of Industrial-Scale Production of Chitosan Microbeads Modified with TiO2 Nanoparticles. [PDF]

open access: yesBiomolecules, 2021
Meramo-Hurtado S   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Using Principles of Inherent Safety for Design of Hydrometallurgical Solvent Extraction Plants

open access: yesChemical Engineering Transactions, 2013
An Inherently Safe (IS) facility relies on the reduction or elimination of hazardous materials or processes through changes in the chemistry, physics and physical design of a process rather than by relying entirely on layers of add-on protection.
L. Moore
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Summary of the proceedings of the Mars Surface Sample Return Symposium [PDF]

open access: yes
A summary is made of various technical and scientific aspects of a Mars surface sample return mission. Particular attention was focused on the question of back contamination.
Devincenzi, D. L., Macelroy, R. D.
core   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Asymptotic safety in the f(R) approximation

open access: yes, 2013
In the asymptotic safety programme for quantum gravity, it is important to go beyond polynomial truncations. Three such approximations have been derived where the restriction is only to a general function f(R) of the curvature R>0. We confront these with
Dietz, Juergen A., Morris, Tim R.
core   +2 more sources

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