Results 71 to 80 of about 216,745 (256)

Prediction of Welding Deformation and Residual Stress Elastic FEM Based on Inherent Strain

Journal of the Society of Naval Architects of Japan, 1996
The welding residual stress and the distortion are considered to be produced by the inherent strain. The plastic strain in a bead welding computed through the thermal-elastic-plastic analysis is an ideal example of the inherent strain, since there is no glove which may introduce additional mismatch.
Hidekazu Murakawa, Yu Luo, Yukio Ueda
openaire   +4 more sources

Distortion Analysis of SLM Product of SS316L using Inherent Strain Method

IOP Conference Series: Materials Science and Engineering, 2020
Abstract As one of additive manufacturing (AM) technologies, selective laser melting (SLM) which uses higher energy input enabling fully molten powder bed materials is nowadays increasingly applied to build full dense components without post processing.
Thoufeili Taufek, Yupiter HP Manurung, Stephan Lüder, Marcel Graf, Farrahshaida Mohd. Salleh   +4 more
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Predicting welding deformation of panel structure using inherent strain method with consideration of structural restraint

Results in Engineering
With the growing focus on welding deformation in the lightweight manufacturing of transportation vehicles, such as ships and automobiles, there has been an increasing demand in the industrial sector for developing inherent strain method using commercial ...
Wei Liang, Zhixu Mao, Dean Deng
doaj   +1 more source

Predicting Welding Distortion in a Panel Structure with Longitudinal Stiffeners Using Inherent Deformations Obtained by Inverse Analysis Method

The Scientific World Journal, 2014
Welding-induced deformation not only negatively affects dimension accuracy but also degrades the performance of product. If welding deformation can be accurately predicted beforehand, the predictions will be helpful for finding effective methods to ...
Wei Liang, Hidekazu Murakawa
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Numerical investigation of welding deformation diminution for double shell structure using the layered inherent strain

Nuclear Engineering and Technology
Cyclotron is a key scientific tool and indispensable research platform for conducting cutting-edge research in nuclear equipment development as well as innovative applications of nuclear technology.
Cheng Li, Hua Zhai, Lianwei Zhu, Zhihong Liu, Jianguo Ma, Xiaofeng Zhu, Qiong Liu   +6 more
doaj   +1 more source