Results 21 to 30 of about 167,700 (213)
Numerical Simulation Study on Welding Process of Upper Frame of Hydropower Unit
Applied SciencesTo optimize the welding process of the upper frame of the hydropower unit, a thermal elastic–plastic (TEP) finite element model of the typical T-joint of the upper frame was established, and the effectiveness and accuracy of the model were verified by ...
Chenlei Yu +4 more
doaj +1 more source
Applied Sciences, 2019 With the rise of electric vehicles, the use of battery modules, which are key units that drive vehicles, is increasing. The battery housing is the final form of a battery system mounted on electric vehicles, and is generally made of aluminum alloys ...
Sungwook Kang +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Journal of Marine Science and EngineeringIntegrated heating and mechanical rolling forming (IHMRF) has recently been introduced for manufacturing complex curvature hull plates. It fabricates the target curved plate by sequential loading along the multipath.
Zhenshuai Wei +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thermal distortion analysis method for TMCP steel structures using shell element
International Journal of Naval Architecture and Ocean Engineering, 2009 As ships become larger, thicker and higher tensile steel plate are used in shipyard. Though special chemical compositions are required for high-tensile steels, recently they are made by the TMCP (Thermo-Mechanical control process) methodology.
Yunsok Ha, S.R. Rajesh
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Applied SciencesResidual stresses and distortions are critical challenges in laser beam powder bed fusion (PBF-LB) of Ti6Al4V components (PBF-LB/M/Ti6Al4V), impacting structural integrity and dimensional accuracy.
Hassan Ali +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source