Results 41 to 50 of about 155,753 (276)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
냉각 시 외적 구속 조건을 고려한 개선된 등가변형도법 기반 용접 해석에 관한 연구 [PDF]
, 2014 학위논문 (박사)-- 서울대학교 대학원 : 조선해양공학과, 2014. 2. 장범선.The prediction and control of welding deformation at design stage has been an essential task in shipbuilding industry to ensure high fabrication quality as well as high productivity.
김태준
core
Numerical Simulation Study on Welding Process of Upper Frame of Hydropower Unit
Applied SciencesTo optimize the welding process of the upper frame of the hydropower unit, a thermal elastic–plastic (TEP) finite element model of the typical T-joint of the upper frame was established, and the effectiveness and accuracy of the model were verified by ...
Chenlei Yu +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2022 Additive manufacturing (AM) of metallic parts is widely utilized for industrial applications. However, quality issues of the printed parts, including part distortion and cracks caused by high temperature and fast cooling, result in high residual stress ...
Hong-Seok Park +4 more
core +1 more source
Thermal distortion analysis method for TMCP steel structures using shell element
International Journal of Naval Architecture and Ocean Engineering, 2009 As ships become larger, thicker and higher tensile steel plate are used in shipyard. Though special chemical compositions are required for high-tensile steels, recently they are made by the TMCP (Thermo-Mechanical control process) methodology.
Yunsok Ha, S.R. Rajesh
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modified Inherent Strain Method for Predicting Residual Deformation in Metal Additive Manufacturing [PDF]
, 2020 Additive manufacturing (AM) of metal components has seen rapid development in the past decade, since arbitrarily complex geometries can be manufactured by this technology. Due to intensive heat input in the laser-assisted AM process, large thermal strain
Liang, Xuan
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source