Results 1 to 10 of about 1,049,137 (382)

Molecular mechanisms of transgenerational epigenetic inheritance

Nature reviews genetics, 2022
Maximilian Fitz-James, Giacomo Cavalli
openalex   +3 more sources

Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis

Nature Communications, 2021
22G-RNAs are single-stranded antisense small RNAs that are expressed in C. elegans germline. Here the authors show that CSR-1 dependent 22G-RNAs are produced in the cytosol on mRNAs actively engaged in translation and that codon usage of an mRNA ...
Meetali Singh, Eric Cornes, Blaise Li, Piergiuseppe Quarato, Loan Bourdon, Florent Dingli, Damarys Loew, Simone Proccacia, Germano Cecere   +8 more
doaj   +1 more source

Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos

Nature Communications, 2021
In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.
Piergiuseppe Quarato, Meetali Singh, Eric Cornes, Blaise Li, Loan Bourdon, Florian Mueller, Celine Didier, Germano Cecere   +7 more
doaj   +1 more source

SSR molecular marker developments and genetic diversity analysis of Zanthoxylum nitidum (Roxb.) DC

Scientific Reports, 2023
Zanthoxylum nitidum (Roxb.) is a commonly used traditional Chinese medicine. However, the collection and protection of wild germplasm resources of Z. nitidum are still insufficient, and there is limited research on its genetic diversity and fingerprint ...
Yanxia Zhu, Tao Ma, Yang Lin, Yude Peng, Yuan Huang, Jianping Jiang   +5 more
doaj   +1 more source

Meroterpenoid Dimers from Ganoderma Mushrooms and Their Biological Activities Against Triple Negative Breast Cancer Cells

Frontiers in Chemistry, 2022
(±)-Dimercochlearlactones A−J (1–10), ten pairs of novel meroterpenoid dimers and one known spirocochlealactone A (11), were isolated from Ganoderma mushrooms.
Fu-Ying Qin, Yan-Yi Chen, Jiao-Jiao Zhang, Yong-Xian Cheng, Yong-Xian Cheng   +4 more
doaj   +1 more source

Influence of Multi-Frequency Ultrasound Treatment on Conformational Characteristics of Beef Myofibrillar Proteins with Different Degrees of Doneness

Foods, 2023
This study evaluated the effect of multi-frequency sonication (20 kHz, 25 kHz, 28 kHz, 40 kHz, 50 kHz) on structural characteristics of beef myofibrillar proteins (MPs) with different degrees of doneness (Rare 52~55 °C, Medium Rare 55~60 °C, Medium 60~65
Zhaoli Zhang, Tingxuan Yang, Yang Wang, Jiarui Liu, Wangbin Shi, Haochen Hu, Yang Meng, Xiangren Meng, Ronghai He   +8 more
doaj   +1 more source

Global Run-On sequencing to measure nascent transcription in C. elegans

STAR Protocols, 2021
Summary: Global Run-On sequencing (GRO-seq) is one of the most sensitive techniques to detect nascent transcription from RNA polymerase (Pol) at a genome-wide level.
Piergiuseppe Quarato, Germano Cecere
doaj   +1 more source

Racemic Norlignans as Diastereoisomers from Ferula sinkiangensis Resins with Antitumor and Wound-Healing Promotion Activities

Molecules, 2022
Ferulasinkins A–D (1–4), four new norlignans, were isolated from the resins of Ferula sinkiangensis, a medicinal plant of the Apiaceae family. All of them were obtained as racemic mixtures, chiral HPLC was used to produce their (+)- and (−)-antipodes ...
Ying-Shi Li, Bao-Chen Yang, Shu-Min Zheng, Yong-Xian Cheng, Hong-Hua Cui   +4 more
doaj   +1 more source

Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders

Nucleic Acids Res., 2004
Online Mendelian Inheritance in Man (OMIM™) is a comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.
A. Hamosh, A. F. Scott, J. Amberger, Carol A. Bocchini, V. McKusick   +4 more
semanticscholar   +1 more source

Changes in Textural Quality and Water Retention of Spiced Beef under Ultrasound-Assisted Sous-Vide Cooking and Its Possible Mechanisms

Foods, 2022
The present study investigated the effects of ultrasound (28 kHz, 60 W at 71 °C for 37 min) combined with sous-vide cooking (at 71 °C for 40, 60, 80, 100, 120 min) on the textural quality, water distribution, and protein characteristics of spiced beef ...
Hengpeng Wang, Ziwu Gao, Xiuyun Guo, Sumin Gao, Danxuan Wu, Zongzhen Liu, Peng Wu, Zhicheng Xu, Xiaobo Zou, Xiangren Meng   +9 more
doaj   +1 more source