Results 131 to 140 of about 722,236 (315)
IEEE Access, 2019 Regression testing is an expensive activity and Test Case Prioritization (TCP) acts as an improvement mechanism for it. TCP techniques for object oriented programs need attention and in our study, we explored prioritization of JUnit test cases.
R. Mukherjee, K. S. Patnaik
doaj +1 more source
Genetic Algorithm for Solving Simple Mathematical Equality Problem [PDF]
arXiv, 2013 This paper explains genetic algorithm for novice in this field. Basic philosophy of genetic algorithm and its flowchart are described. Step by step numerical computation of genetic algorithm for solving simple mathematical equality problem will be briefly ...
arxiv
Animal Models and Experimental Medicine, EarlyView.In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang +6 more
wiley +1 more source
VariantAlert: A web‐based tool to notify updates in genetic variant annotations
Human Mutation, Volume 43, Issue 12, Page 1808-1815, December 2022., 2022 Abstract The reinterpretation of variants based on updated annotations is part of the routine work of research laboratories: the more data is collected about a specific variant, the higher the probability to reinterpret its classification. To support this task, we developed VariantAlert, a web‐based tool to help researchers and clinicians to be ...
Rossano Atzeni +3 more
wiley +1 more source
Efficient path-based computations on pedigree graphs with compact encodings
BMC Bioinformatics, 2012 A pedigree is a diagram of family relationships, and it is often used to determine the mode of inheritance (dominant, recessive, etc.) of genetic diseases.
Yang Lei, Cheng En, Özsoyoğlu Z Meral
doaj +1 more source
Annals of Hepatology, 2023 Introduction and Objectives: Alpha-1 antitrypsin (AAT) is an acute-phase glycoprotein encoded by the SERPINA1 gene. This allele has a codominant expression and Alpha-1 antitrypsin deficiency (AATD) is caused by the inheritance of two affected alleles ...
Mariela Solano-Vargas +5 more
doaj
Annals of Neurology, EarlyView.Objective Genetic dystonia is a complex movement disorder with diverse clinical manifestations resulting from pathogenic mutations in associated genes. A recent paradigm shift emphasizes the functional convergence among dystonia genes, hinting at a shared pathomechanism. However, the neural dynamics supporting this convergence remain largely unexplored.
Ahmet Kaymak +18 more
wiley +1 more source
Systemic circulating microRNA landscape in Lynch syndrome
International Journal of Cancer, Volume 152, Issue 5, Page 932-944, 1 March 2023., 2023 What's new? Systemic circulating microRNA expression patterns (c‐miRnomes) are altered during sporadic carcinogenesis and they have predictive potential in early cancer detection. However, their potential in carriers of inherited pathogenic mismatch‐repair gene variants associated with Lynch syndrome remains understudied.
Tero Sievänen +10 more
wiley +1 more source
The new classes of the genetic algorithms are defined by nonassociative groupoids [PDF]
arXiv, 2012 The genetic product of the groupoids, originating in the theory of DNA recombination, is introduced. It permits a natural generalization of the classical genetic algorithm. The full characterization of all three-element genetic groupoids gives an approach to construct the new classes of genetic algorithms.
arxiv
The Anatomical Record, EarlyView.Abstract Craniosynostosis is a common yet complex birth defect, characterized by premature fusion of the cranial sutures that can be syndromic or nonsyndromic. With over 180 syndromic associations, reaching genetic diagnoses and understanding variations in underlying cellular mechanisms remains a challenge.
Heather A. Richbourg +9 more
wiley +1 more source