The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease [PDF]
, 2006 Sickle cell disease (SCD) is one of the most common inherited diseases in the world and the patients present notorious clinical heterogeneity. It is known that patients with SCD present activation of the blood coagulation and fibrinolytic systems ...
Beltrão, A.c.s. +6 more
core +3 more sources
Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism
International Journal of Gynecology &Obstetrics, EarlyView.
Emma Bertucci +10 more
wiley +1 more source
Thrombophilia in young adults with ischemic stroke: an overview
Neurologijos seminarai, 2019 Thrombophilia broadly defines inherited or acquired coagulation disorders associated with increased tendency to form intravascular thrombi. Evaluation for thrombophilia in young patients with cryptogenic stroke is a frequent clinical question.
R. Mineikytė +2 more
doaj +1 more source
Factor V G1691A (Leiden) is a major etiological factor in Egyptian Budd-Chiari syndrome patients [PDF]
, 2011 Objective: Budd-Chiari syndrome is a multifactorial disease in which several prothrombotic disorders may predispose patients to the development of thrombosis at this uncommon location (hepatic veins). The aim of this study was to determine the prevalence
Ezzat S. Elsobky +7 more
core
Comparative frequency of Coagulation Factor II and Coagulation Factor V Alleles among new-born and senior citizens [PDF]
, 2005 Resistance to activated protein C is one of the most common inherited disorders associated with hereditary thrombophilia. A missense mutation in the gene coding for coagulation factor V (CF V Leiden) and which renders this procoagulant factor resistant ...
Abela Medici, Joseph +4 more
core
Blood Advances, 2017 : Routine testing for inherited and acquired thrombophilia defects is frequently performed in pediatric patients with thromboembolic events (TEEs). No consensus guidelines exist regarding the timing of testing or the type of patients to be tested.
Chakri Gavva +2 more
doaj +1 more source
Роль наследственной тромбофилии в развитии хронической фето-плацентарной недостаточности и синдрома внутриутробной задержки роста плода [PDF]
, 2012 В литературном обзоре представлены основные этио- патогенетические аспекты плацентарной недостаточности и ее основного проявления - синдрома внутриутробной задержки роста ...
Зарудская, О. М. +1 more
core +1 more source
Postpartum maternal thrombophilia workup value in pregnancies with severe small for gestational age
Acta Obstetricia et Gynecologica ScandinavicaIntroduction In the absence of prenatal etiology explaining small for gestational age (SGA), a blood workup may be performed postpartum to look for maternal thrombophilia if a newborn is confirmed to be growth‐restricted at birth.
Maëlig Abgral +6 more
doaj +1 more source
The study of normal pregnancy in women with hereditary thrombophilia
Акушерство, гинекология и репродукция, 2016 Objective: The definition of the conditions under which women with inherited thrombophilia can have a positive pregnancy outcome. Materials and Methods.
M. V. Khruslov +5 more
doaj +1 more source
Approaches to detect genetic effects that differ between two strata in genome-wide meta-analyses: Recommendations based on a systematic evaluation. [PDF]
, 2017 Genome-wide association meta-analyses (GWAMAs) conducted separately by two strata have identified differences in genetic effects between strata, such as sex-differences for body fat distribution.
Cupples, L. Adrienne +6 more
core +5 more sources