Results 161 to 170 of about 274,980 (309)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Association Between Type D Personality and Cardiovascular Disease History: Cross-Sectional Study. [PDF]

JMIR Cardio
Grinberg K, Sela Y.
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

Trends in age‐sex‐specific prevalence and incidence of antidepressant dispensation in the Nordic countries: a systematic review

British Journal of Clinical Pharmacology, EarlyView.
Differences in antidepressant dispensation across the Nordic countries have been reported, but existing reviews are based on older data. We conducted a systematic review of population‐based studies reporting prevalence and/or incidence of antidepressant dispensation in the Nordic countries.
Marcel Ballin, Paulina Tuvendal, Carola Bardage, Mats Persson, Mats Talbäck, Rickard Ljung   +5 more
wiley   +1 more source

Profiling decision-making mechanisms in binge eating disorder. [PDF]

J Eat Disord
Colton E, Agosta C, Carey H, Giddens E, Noy B, Flanagan K, Tsyrlin L, Wilson KE, Pacheco LB, Mahlberg J, Chong TT, Verdejo-Garcia A.   +11 more
europepmc   +1 more source

The relationship between social media emotional contagion and reactive aggression for late adolescence: the mediating effect of Behavioral Activation System(BAS)/Behavioral Inhibition System(BIS). [PDF]

BMC Psychol
Cho Y, Park W.
europepmc   +1 more source

Individual differences in cognitive control modulate cognitive biases linked to depressive symptoms [PDF]

, 2016
Everaert, Jonas, Grahek, Ivan, Koster, Ernst   +2 more
core   +2 more sources