Results 121 to 130 of about 4,033,279 (373)
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Integration and regulation of glomerular inhibition in the cerebellar granular layer circuit
Frontiers in Cellular Neuroscience, 2014 Inhibitory synapses can be organized in different ways and be regulated by a multitude of mechanisms. One of the best known examples is provided by the inhibitory synapses formed by Golgi cells onto granule cells in the cerebellar glomeruli.
Lisa eMapelli +5 more
doaj +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Frontiers in Psychology, 2019 This study investigated the underlying cognitive abilities which are related to both fluency in reading and arithmetic across different developmental phases of their acquisition.
Reut Balhinez, Shelley Shaul
doaj +1 more source
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.
Cancer Research, 2006 Stimulation of the insulin and insulin-like growth factor I (IGF-I) receptor activates the phosphoinositide-3-kinase/Akt/mTOR pathway causing pleiotropic cellular effects including an mTOR-dependent loss in insulin receptor substrate-1 expression leading
K. O'reilly +11 more
semanticscholar +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Selective attention and inhibition in young school-aged children [PDF]
Specijalna Edukacija i Rehabilitacija, 2019 The aims of this research were to determine the developmental dynamics of selective attention and inhibition in younger school-aged children, as well as its relationship with gender and intellectual abilities.
Gligorović Milica, Buha Nataša
doaj
Inhibitory motor control in old age: evidence for de-automatization?
Frontiers in Psychology, 2011 To examine age-related effects on high-level consciously-controlled and low-level automatically-controlled inhibitory processes, the Simon task was combined with the masked prime task in a hybrid procedure.
Elizabeth Ann Maylor +2 more
doaj +1 more source
Inhibition of Transport of Indole-3-Acetic Acid in the Etiolated Hypocotyl of Phaseolus Vulgaris L. [PDF]
, 1956 JA Zwar, AHGC Rijven
openalex +1 more source