Results 271 to 280 of about 4,778,507 (336)

One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression. [PDF]

Cancer Res Commun
Zirpoli S, Copperman N, Patel S, Forrest A, Hou Z, Matherly LH, Loeb DM, Di Cristofano A.   +7 more
europepmc   +1 more source

S-ADENOSYLETHIONINE AND ETHIONINE INHIBITION

, 1958
Leo W. Parks
openalex   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Protein arginine methyltransferase 5 sustains Tip60-EP400 complex via SRSF1 in Merkel cell carcinoma. [PDF]

Life Sci Alliance
Sevigny JL, Proctor EV, Adams H, MacDonald ER, Thomas WK, Cheng J.   +5 more
europepmc   +1 more source

THE INHIBITION OF TOBACCO MOSAIC VIRUS BY SYNTHETIC LYSINE POLYPEPTIDES

, 1951
Mark A. Stahmann, Liselotte Graf, Eleanor Patterson, J. C. Walker, Dennis W. Watson   +4 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Therapeutic Potential of Stylissatin A and Related Cyclic Peptides From Marine Sponges. [PDF]

J Pept Sci
Ullah A, Shaheen F, Salar U, Tzakos AG, Gerothanassis IP.   +4 more
europepmc   +1 more source