Results 271 to 280 of about 6,398,774 (357)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Exosome-mediated decay of unstable long extended precursors of human telomerase RNA is dependent on 5'-cap trimethylation. [PDF]

Genes Dev
Samajdar A, Amato R, Jo S, Cordes E, Tai A, Raffa GD, Batista LFZ.   +6 more
europepmc   +1 more source

Selective anticancer activity of <i>Vachellia nilotica</i> fruit extract: integrated phytochemistry with antioxidant, antimicrobial, and cancer cell targeting. [PDF]

Front Nutr
Abdul-Hafeez EY, Ibrahim OHM, Alfheeaid HA, Barakat H.   +3 more
europepmc   +1 more source

Carotenoid nanoforms from clementine peel stabilized by xanthan and arabic gums with antioxidant anti inflammatory and antimicrobial activities. [PDF]

Sci Rep
Ahmed HA, Ibrahim EA, Salama ZA, Abd-El Fatah SI.   +3 more
europepmc   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions. [PDF]

Pharmacol Res Perspect
Hosseini SA, Valadbeigi H, Khoshnazar SM, Khoshnood S, Falahi S, Rezaee D, Hematian A, Haddadi MH.   +7 more
europepmc   +1 more source

Metabolic drivers of genome instability in cancer: mechanisms and therapeutic opportunities. [PDF]

Exp Hematol Oncol
Wang YS, Qian LH, Liu CC, Yu KD.
europepmc   +1 more source

Correction to "Inhibition of STAT3 by S3I-201 Suppress Peritoneal Fibroblast Phenotype Conversion and Alleviate Peritoneal Fibrosis". [PDF]

J Cell Mol Med
europepmc   +1 more source

Correction to “Altered splicing of ATG16‐L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non‐small cell lung cancer”

Molecular Oncology, EarlyView.
wiley   +1 more source