Results 291 to 300 of about 4,778,507 (336)

Herbicide dose-response thresholds in sands to assess the risk of non-target damage to winter grain crops. [PDF]

PLoS One
Pyone WW, Bell RW, Rose MT, McGrath GS.
europepmc   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Genetically proxied inhibition of Phosphodiesterase-5 and cancer risks: A drug-target Mendelian randomization analysis. [PDF]

Sci Rep
Tang K, Li B, Wu X, Wang M.
europepmc   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Weak Acids as Endogenous Inhibitors of the Proton-Activated Chloride Channel. [PDF]

Cells
Pombeiro Stein ICA, Schulz M, Rudolf D, Herzog C, Echtermeyer F, Kriedemann N, Zweigerdt R, Leffler A.   +7 more
europepmc   +1 more source

Commentary: The ETP-based APC resistance assay remains the gold standard for evaluating the APC resistance phenotype in users of combined oral contraceptives. [PDF]

Front Cardiovasc Med
Morimont L, Douxfils J.
europepmc   +1 more source

Corrigendum to "Inhibition of Mitofusin-2 Promotes Cardiac Fibroblast Activation via the PERK/ATF4 Pathway and Reactive Oxygen Species". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source