Results 11 to 20 of about 4,357,014 (211)

AKT activation controls cell survival in response to HDAC6 inhibition. [PDF]

, 2016
HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor.
Aboagye, EO, Ali, T, Kaliszczak, M, Trousil, S   +3 more
core   +1 more source

A 1-acetamido derivative of 6-epi-valienamine: an inhibitor of a diverse group of β-N-acetylglucosaminidases [PDF]

, 2007
The synthesis of an analogue of 6-epi-valienamine bearing an acetamido group and its characterisation as an inhibitor of β-N-acetylglucosaminidases are described.
Adrian Scaffidi, Backvall, Bailey, Beer, Chen, Chretien, David J. Vocadlo, Davies, Davies, Dennis, Dong, Dorfmueller, Edward J. Taylor, Emsley, Esnouf, Fairweather, Gideon J. Davies, Horsch, Junge, Kappes, Keith A. Stubbs, Knapp, Kraulis, Legler, Lin, Liu, Liu, Macauley, Mark, Money, Murshudov, Namiki, Nicotra, Ogawa, Rana, Rao, Rebecca J. Dennis, Robert V. Stick, Salleh, Scaffidi, Shanmugasundaram, Shitara, Sigurskjold, Stubbs, Stubbs, Svensson, Tanaka, Terinek, Tews, Vocadlo   +49 more
core   +1 more source

PEMANFAATAN EKSTRAK DAUN RAMBUTAN SEBAGAI INHIBITOR KOROSI PADA PLAT BESI DALAM MEDIA AIR PAYAU

Chemical Engineering Journal Storage, 2022
Abstrak Korosi adalah peristiwa kerusakan atau penurunan mutu suatu logam akibat reaksi elektrokimia dengan lingkungannya. Penanganan masalah korosi dapat dilakukan dengan menambahkan inhibitor korosi dari ekstrak daun rambutan yang mengandung tanin dan
Rizzki Andira, Zulnazri Zulnazri, Syamsul Bahri, Azhari Azhari, Agam Muarif   +4 more
doaj   +1 more source

Developments in plant breeding for improved nutritional quality of soya beans II. Anti-nutritional factors [PDF]

, 2000
Nutritional value of most plant materials is limited by the presence of numerous naturally occurring compounds which interfere with nutrient digestion and absorption.
Clarke, E, Wiseman, J
core   +1 more source

Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]

, 2004
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M, Deck, Lorraine M, Heidrich, John E, Hunsaker, Lucy A, Vander Jagt, David L   +4 more
core   +2 more sources

Second-line antiretroviral therapy in resource-limited settings: the experience of Médecins Sans Frontières [PDF]

, 2008
OBJECTIVES: To describe the use of second-line protease-inhibitor regimens in Médecins Sans Frontières HIV programmes, and determine switch rates, clinical outcomes, and factors associated with survival.
Alexandra Calmy, Boyd, Braitstein, Calmy, Calmy, Chaiwarith, Colebunders, Daniel O'Brien, Ferradini, Gallant, Galárraga, Ivers, Laurent, Ledergerber, Mar Pujades-Rodríguez, Mocroft, Nicastri, Orrell, Pierre Humblet, Renaud-Théry, Srasuebkul, Sungkanuparph, Vasan, Vekemans, Walmsley   +24 more
core   +2 more sources

Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals

Viruses, 2020
Human immunodeficiency virus 1 (HIV-1) is the most prevalent human retrovirus. Recent data show that 34 million people are living with HIV-1 worldwide.
Gavin C. Sampey, Sergey Iordanskiy, Michelle L. Pleet, Catherine DeMarino, Fabio Romerio, Renaud Mahieux, Fatah Kashanchi   +6 more
doaj   +1 more source

The role and action mechanism of inhibitors in solutions for etching steel

Zaštita Materijala, 2015
Acid etching has a major task, regardless of which acid is used, to cancel all corrosion products from objects before it starts to erode base material.
Bosiljka Ljubičić, Saša Mićin
doaj   +1 more source

Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors

Frontiers in Chemistry, 2022
The COVID-19 pandemic continues unabated, emphasizing the need for additional antiviral treatment options to prevent hospitalization and death of patients infected with SARS-CoV-2.
Dale J. Calleja, Nathan Kuchel, Bernadine G. C. Lu, Richard W. Birkinshaw, Theresa Klemm, Marcel Doerflinger, James P. Cooney, Liana Mackiewicz, Amanda E. Au, Yu Q. Yap, Timothy R Blackmore, Kasiram Katneni, Elly Crighton, Janet Newman, Kate E. Jarman, Melissa J. Call, Bernhard C. Lechtenberg, Peter E. Czabotar, Marc Pellegrini, Susan A. Charman, Kym N. Lowes, Jeffrey P. Mitchell, Ueli Nachbur, Guillaume Lessene, Guillaume Lessene, David Komander   +25 more
doaj   +1 more source

The roles of p38mAPK and caspase-3 in dads-induced apoptosis in human HepG2 cells [PDF]

Archives of Biological Sciences, 2010
The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells were investigated. After the human HepG2 cells were treated with DADS, the cell viability, apoptosis and the activity changes of p38MAPK and caspase-3 were measured.
Chunxiao Ji, Heng Ma, Ren Fenglian
doaj   +1 more source