Results 21 to 30 of about 3,476,202 (307)
The role and action mechanism of inhibitors in solutions for etching steel
Acid etching has a major task, regardless of which acid is used, to cancel all corrosion products from objects before it starts to erode base material.
Bosiljka Ljubičić, Saša Mićin
doaj +1 more source
بوليميرازات بولي (ADP - ريبوز)، التي يتم اختصارها باسم PARPs، هي مجموعة من البروتينات المألوفة التي تلعب دورًا مركزيًا في إصلاح الحمض النووي باستخدام مسار إصلاح استئصال القاعدة (BER). هناك حوالي 17 بروتينًا في هذه العائلة منها PARPs النووية الأولية هي PARP -1 و PARP -2 و PARP -3 و tankyrases 1 و 2 (PARP -5a و -5b).
Maheen Anwar +2 more
openaire +2 more sources
Berdasarkan berbagai penelitian, kulit manggis memiliki potensi yang baik sebagai inhibitor korosi Tujuan dari penelitian ini adalah untuk mengetahui efisiensi ekstrak inhibitor kulit manggis pada baja lunak dalam larutan asam sulfat.
Marta Pramudita +2 more
doaj +1 more source
High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase
Ceramide has a key role in the regulation of cellular senescence and apoptosis. As Ceramide levels are lowered by the action of acid ceramidase (AC), abnormally expressed in various cancers, the identification of AC inhibitors has attracted increasing ...
Mazen Aseeri +5 more
doaj +1 more source
The Effect of NAG–thiazoline on Morphology and Surface Hydrophobicity of Escherichia Coli [PDF]
The β-hexosaminidase inhibitor and structural analog of the putative oxazolium reaction intermediate of lytic transglycosylases, N-acetylglucosamine thiazoline (NAG–thiazoline), was synthesized in 46% overall yield and tested as an inhibitor of ...
Blackburn, Neil T. +2 more
core +2 more sources
Schistosoma mansoni is an intestinal parasite with one β-class carbonic anhydrase, SmaBCA. We report the sequence enhancing, production, catalytic activity, and inhibition results of the recombinant SmaBCA. It showed significant catalytic activity on CO2
Susanna Haapanen +5 more
doaj +1 more source
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
Structural tailoring of the flavone framework (position 7) via organopalladium-catalyzed C–C bond formation was attempted in this study. The impact of substituents with varied electronic effects (phenyl ring, position 2 of the benzopyran scaffold) on the
Sachin Sharma +11 more
doaj +1 more source
Acute myeloid leukemia (AML) cells harbor elevated levels of reactive oxygen species (ROS), which promote cell proliferation and cause oxidative stress. Therefore, the inhibition of ROS formation or elevation beyond a toxic level have been considered as ...
Muhammed Burak Demircan +6 more
doaj +1 more source
Farnesyltransferase inhibitors
The targeting of molecular abnormalities in neoplasms may provide an opportunity to improve the selectivity of cancer therapy. Ras mutations are a common genetic event in human cancers. Other genetic changes in tumors can signal through ras-dependent pathways as well.
Hahn, S, Bernhard, E, Mckenna, W
openaire +3 more sources
Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring. [PDF]
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from
Boulle, A +18 more
core +4 more sources

