Results 41 to 50 of about 765,759 (204)
Cancer Treatment and Research Communications, 2022 Malignant rhabdoid tumour (MRT) is a rare, aggressive paediatric malignancy most commonly diagnosed in those below the age of three. MRTs can arise in soft tissue but are more often associated with the central nervous system or kidney. Unfortunately, the
Rachel Coyle +2 more
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Targeting BCL-2 regulated apoptosis in cancer [PDF]
, 2018 The ability of a cell to undergo mitochondrial apoptosis is governed by pro- and anti-apoptotic members of the BCL-2 protein family. The equilibrium of pro- versus anti-apoptotic BCL-2 proteins ensures appropriate regulation of programmed cell death ...
Campbell, Kirsteen J. +1 more
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Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin
FEBS Open Bio, 2015 Shiga toxin (Stx) causes fatal systemic complications. Stx induces apoptosis, but the mechanism of which is unclear. We report that Stx induced rapid reduction of short‐lived anti‐apoptotic proteins followed by activation of caspase 9 and the progression
Takayuki Hattori +6 more
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Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]
, 2017 Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana +5 more
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Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Objective To investigate the effect of astragaloside Ⅳ on the injury of SK⁃N⁃SH cell in Parkinson's disease (PD) induced by 1 ⁃ methy ⁃ 4 ⁃ phenylpyridine (MPP＋) and its mechanism.
HUANG Xiao⁃jing +5 more
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Transcriptome dynamics in the asexual cycle of the chordate Botryllus schlosseri [PDF]
, 2016 Background: We performed an analysis of the transcriptome during the blastogenesis of the chordate Botryllus schlosseri, focusing in particular on genes involved in cell death by apoptosis. The tunicate B.
Ballarin, Loriano +7 more
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Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]
, 2020 Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P. +7 more
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miR-142-3p inhibits cerulein-induced apoptosis of rat pancreatic exocrine cell line AR42J by regulating Hmgb1 [PDF]
Jichu yixue yu linchuangObjective To investigate the effect of miR-142-3p on the apoptosis of rat pancreatic exocrine cell line AR42J by regulating Hmgb1. Methods AR42J cells were divided into blank group (blank), acute pancreatitis model group (AP, 100 nmol/L cerulein for 24 h)
SU Shixiang, WANG Yuyang, QIN Zongshuai, HUANG Guixiang, XU Jian, CEN Lanying, QIN Yueqiu
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Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9 [PDF]
Proceedings of the National Academy of Sciences, 2000 We cloned a new inhibitor of apoptosis protein (IAP) homolog, SfIAP, from Spodoptera frugiperda Sf-21 cells, a host of insect baculoviruses. SfIAP contains two baculovirus IAP repeat domains followed by a RING domain.
Q, Huang +6 more
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Targeting Inhibitor of Apoptosis Proteins to Block Vascular Inflammation [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011 The tumor necrosis factor (TNF) receptor superfamily (TNFRSF) represents a large number of membrane-bound and secreted proteins that regulate inflammation and other functions in the vasculature and other tissues. Members of the TNFRSF are involved in the pathogenesis of atherosclerosis,1 and treatment with anti-TNFα antibodies enhances vascular ...
Le Anh, Luong, Paul C, Evans
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