Results 151 to 160 of about 5,057,415 (322)
Studies on ali-esterases. 4. Differentiation of esterases in pancreas and brain by the use of organophosphorus inhibitors [PDF]
, 1956 D. K. Myers
openalex +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Bacterial Inhibitors for Cutting Oil [PDF]
, 1956 H. O. Wheeler, E. O. Bennett
openalex +2 more sources
A Procedure Which Eliminates Nonspecific Inhibitor from Human Serum But does not Affect Specific Antibodies Against Influenza Viruses [PDF]
, 1952 D. A. J. Tyrrell, Frank L. Horsfall
openalex +1 more source
Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance
Nature Reviews Clinical Oncology, 2019 F. Martins +16 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
E(3)-invariant diffusion model for pocket-aware peptide generation [PDF]
arXivBiologists frequently desire protein inhibitors for a variety of reasons, including use as research tools for understanding biological processes and application to societal problems in agriculture, healthcare, etc. Immunotherapy, for instance, relies on immune checkpoint inhibitors to block checkpoint proteins, preventing their binding with partner ...
arxiv
IDENTIFICATION OF THE TRYPSIN INHIBITOR OF EGG WHITE WITH OVOMUCOID
, 1947 Hans Lineweaver, Christopher Murray
openalex +1 more source
THE SITE OF INHIBITION OF BLOOD CLOTTING BY SOY BEAN TRYPSIN INHIBITOR 1 [PDF]
, 1951 Mary Beth Glendening, Ernest W. Page
openalex +1 more source
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source