Results 291 to 300 of about 6,512,999 (388)

THE EFFECT OF INHIBITORS ON SUCCINOXIDASE

, 1937
V.R. Potter, C.A. Elvehjem
openalex   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Breaking Cancer's Momentum: CDK4/6 Inhibitors and the Promise of Combination Therapy. [PDF]

Cancers (Basel)
Liu Y, Park S, Li Y.
europepmc   +1 more source

On the existence of a growth-inhibiting substance in the Chinese lemon /

, 1919
Howard S. Reed, Frederick Ferdinand Halma   +1 more
openalex   +2 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

The Role of Immunotherapy and Immune Modulators in Hormone-Positive Breast Cancer: Implications for Localized and Metastatic Disease. [PDF]

J Clin Med
O'Farrell J, Lapp C, Kuznia H, Afzal MZ.
europepmc   +1 more source

Further Studies with Xanthine Oxidase Inhibitors

, 1959
W.W. Westerfeld, Dan A. Richert, Edwin S. Higgins   +2 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Role of <i>TERT</i> gene mutation in the pathogenesis of anaplastic thyroid carcinoma (Review). [PDF]

Mol Clin Oncol
Alhejaily AG, Alhuzaim O, Aljohani N, Alghamdi D, Salem RO.   +4 more
europepmc   +1 more source

The mechanisms of motor end‐plate depolarization due to a cholinesterase‐inhibiting drug

, 1954
W. W. Douglas, W. D. M. Paton
openalex   +2 more sources