Results 311 to 320 of about 3,954,159 (357)
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The Lancet, 2001
Vasopeptidase inhibitors are a new class of cardiovascular drug that simultaneously inhibit both neutral endopeptidase and angiotensin-converting enzyme (ACE). They increase the availability of peptides that have vasodilatory and other vascular effects; they also inhibit production of angiotensin II.
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Vasopeptidase inhibitors are a new class of cardiovascular drug that simultaneously inhibit both neutral endopeptidase and angiotensin-converting enzyme (ACE). They increase the availability of peptides that have vasodilatory and other vascular effects; they also inhibit production of angiotensin II.
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Current Oncology Reports, 2000
Angiogenesis inhibitors target the neovascular development that is hypothesized to underlie tumor growth. The inhibitors that are undergoing the clinical testing phase can be divided into five categories based on their target activity: 1) drugs that block matrix breakdown; 2) drugs that inhibit endothelial cells directly; 3) drugs that block ...
T R, Tennant +2 more
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Angiogenesis inhibitors target the neovascular development that is hypothesized to underlie tumor growth. The inhibitors that are undergoing the clinical testing phase can be divided into five categories based on their target activity: 1) drugs that block matrix breakdown; 2) drugs that inhibit endothelial cells directly; 3) drugs that block ...
T R, Tennant +2 more
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2016
Lysine acetylation in proteins is one of the most abundant posttranslational modifications in eukaryotic cells. The dynamic homeostasis of lysine acetylation and deacetylation is dictated by the action of histone acetyltransferases (HAT) and histone deacetylases (HDAC).
Heidi, Olzscha +3 more
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Lysine acetylation in proteins is one of the most abundant posttranslational modifications in eukaryotic cells. The dynamic homeostasis of lysine acetylation and deacetylation is dictated by the action of histone acetyltransferases (HAT) and histone deacetylases (HDAC).
Heidi, Olzscha +3 more
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Medicina Clínica (English Edition), 2016
Pharmacological inhibition of the kinase activity of JAK proteins can interfere with the signaling of immunomodulatory cytokines and block the constitutive activation of the JAK-STAT pathway that characterizes certain malignancies, including chronic myeloproliferative neoplasms.
Juan Carlos, Hernández Boluda +2 more
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Pharmacological inhibition of the kinase activity of JAK proteins can interfere with the signaling of immunomodulatory cytokines and block the constitutive activation of the JAK-STAT pathway that characterizes certain malignancies, including chronic myeloproliferative neoplasms.
Juan Carlos, Hernández Boluda +2 more
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2018
Advances in the field of corrosion inhibitors proceed in two main directions: (i) development of eco-friendly effective treatments and (ii) production of “smart” coatings. The first issue is connected to the more strict regulations regarding corrosion inhibitors application, due to environmental concerns.
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Advances in the field of corrosion inhibitors proceed in two main directions: (i) development of eco-friendly effective treatments and (ii) production of “smart” coatings. The first issue is connected to the more strict regulations regarding corrosion inhibitors application, due to environmental concerns.
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Nursing Clinics of North America, 2016
Antithrombotic medications have become standard of care for management of acute coronary syndrome. Platelet adhesion, activation, and aggregation are essential components of platelet function; platelet-inhibiting medications interfere with these components and reduce incidence of thrombosis.
Megan M, Shifrin, S Brian, Widmar
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Antithrombotic medications have become standard of care for management of acute coronary syndrome. Platelet adhesion, activation, and aggregation are essential components of platelet function; platelet-inhibiting medications interfere with these components and reduce incidence of thrombosis.
Megan M, Shifrin, S Brian, Widmar
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Enzymatic Inhibitors (Protease inhibitors, Amylase inhibitors, Cholinesterase Inhibitors)
2022Varun Kumar, Kanwate Balaji
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Cellular and Molecular Life Sciences, 2015
Autophagy is a lysosome-dependent mechanism of intracellular degradation. The cellular and molecular mechanisms underlying this process are highly complex and involve multiple proteins, including the kinases ULK1 and Vps34. The main function of autophagy is the maintenance of cell survival when modifications occur in the cellular environment.
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Autophagy is a lysosome-dependent mechanism of intracellular degradation. The cellular and molecular mechanisms underlying this process are highly complex and involve multiple proteins, including the kinases ULK1 and Vps34. The main function of autophagy is the maintenance of cell survival when modifications occur in the cellular environment.
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Oncology Reports, 1996
A number of proteins and low-molecular weight compounds have been reported to suppress the activity toward ras-oncogenes and their products. These include anti-lias antibody, inhibitors of Ras activation, Ras dominant negative mutants, inhibitors of processing of newly-synthesized Ras, suppressors and inhibitors of downstream effecters and genetic ...
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A number of proteins and low-molecular weight compounds have been reported to suppress the activity toward ras-oncogenes and their products. These include anti-lias antibody, inhibitors of Ras activation, Ras dominant negative mutants, inhibitors of processing of newly-synthesized Ras, suppressors and inhibitors of downstream effecters and genetic ...
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Seminars in Hematology, 2006
The majority of direct costs associated with caring for patients with hemophilia are attributed to replacement therapy with clotting factor concentrates (CFC). For patients who develop high-titer inhibitors, CFC are ineffective and bypassing therapy is used to achieve hemostasis, thus changing the direct costs associated with treatment.
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The majority of direct costs associated with caring for patients with hemophilia are attributed to replacement therapy with clotting factor concentrates (CFC). For patients who develop high-titer inhibitors, CFC are ineffective and bypassing therapy is used to achieve hemostasis, thus changing the direct costs associated with treatment.
openaire +2 more sources