Results 131 to 140 of about 7,577,140 (312)
List of ligands studied for their IDE inhibitory activity.
, 2015 List of ligands studied for their IDE inhibitory activity.
Sonali Gopichand Chavan (713710) +1 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Structures of Compounds Showing Inhibitory Activity against BACE-1.
, 2012 Structures of Compounds Showing Inhibitory Activity against BACE-1.
Li-Hua Zhou (160227) +3 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
, 2019 Introduction: Yersinia enterocolitica is a major source of food poisoning via the consumption of contaminated meat products, causing acute gastroenteric yersiniosis.
Lee, Cameron Jay +4 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibitory activity of periplasmic extracts of different APEC strains.
, 2012 *Experiments were performed in triplicate and mean inhibitory activity (IU/ml) and standard deviation are shown. Since MliC is a membrane protein, its activity can not be measured in a periplasmic extract.a Inhibitory activity differing ...
Chris W. Michiels (43465) +5 more
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Medical Journal of BabylonBackground: Vaginitis is inflammation of the vagina caused by a disruption in the normal vaginal flora. Objectives: This research aims to study the inhibitory activity of raw grapefruit juice, alcoholic, and aqueous grapefruit peel extract against the ...
Faleeha Habeeb Hussien +2 more
doaj +1 more source