Results 51 to 60 of about 7,577,140 (312)

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Synthesis of N′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase

Applied Sciences, 2021
Nineteen tosylated acyl hydrazone derivatives were synthesized, and their inhibitory activities against monoamine oxidases (MAOs), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-secretase (BACE-1) were evaluated.
Hasan Erdinç Sellitepe, Jong Min Oh, İnci Selin Doğan, Sercan Yildirim, Ahmet Buğra Aksel, Geum Seok Jeong, Ahmed Khames, Mohamed A. Abdelgawad, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew, Hoon Kim   +11 more
doaj   +1 more source

Inhibitory and bactericidal activity of SepECP proteins.

, 2015
aNo Activity.Inhibitory and bactericidal activity of SepECP proteins.
Céline Zatylny-Gaudin (301040), Valérie Cornet (769033), Joël Henry (301050), Gildas Le Corguillé (769035), Emilie Duval (769034), Benoit Bernay (192589), Erwan Corre (449013), Didier Goux (189716)   +7 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Extraction of Polysaccharides from Black Corncob Using Ultrasonic-assisted Deep Eutectic Solvent and Its Activity in Inhibiting α-Glycosidase

Shipin gongye ke-ji
To investigate the extraction method of polysaccharide from black corncob and its inhibitory effect on α-glycosidase, black corncobs were used as the raw material in this study, and polysaccharide from black corncob was extracted using ultrasonic ...
Han YUN, Xi YU, Fangfei LI, Yihong BAO, Yangyang CHAI   +4 more
doaj   +1 more source

Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial infection. [PDF]

, 2010
Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression ...
Martin Vordermeier, Allen, RL, Rachel L. Allen, Pilsbury, LE, Louise E. Pilsbury, Vordermeier, M   +5 more
core   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Thymidine Phosphorylase Inhibitory Activity of Compounds 1–18 (Continued).

, 2019
Thymidine Phosphorylase Inhibitory Activity of Compounds 1–18 (Continued).
M. Iqbal Choudhary (598049), Sumaira Javaid (7886897), Muniza Shaikh (7886900), Narjis Fatima (3778390)   +3 more
core   +3 more sources

Inhibitory KHKC Activity of Candidate Phytochemicals.

, 2016
Inhibitory KHKC Activity of Candidate Phytochemicals.
MyPhuong T. Le (103457), R. Keith Randolph (2847629), Brandi L. Hunter (2847632), Jeffrey D. Scholten (2847623), Miguel A. Lanaspa (119910), Richard J. Johnson (103499), Christopher J. Rivard (119936), Christina M. Cicerchi (2847626), Jatinder Rana (2847635)   +8 more
core   +1 more source