Results 261 to 270 of about 1,832,210 (358)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Inhibitory Effect of Electrolyzed Reduced Water on Tumor Angiogenesis

, 2008
Jun Ye, Yuping Li, Takeki Hamasaki, Noboru Nakamichi, Takaaki Komatsu, Taichi Kashiwagi, Kiichiro Teruya, Ryuhei Nishikawa, Takeshi Kawahara, Kazuhiro Osada, Kazuko Toh, Masumi Abe, Huaize Tian, Shigeru Kabayama, K. Otsubo, Shinkatsu Morisawa, Yoshinori Katakura, Sanetaka Shirahata   +17 more
openalex   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Dietary Polyphenol Combinations Have a Multifaceted Inhibitory Effect on Metabolic Rewiring and Signaling Pathways in Neuroblastoma. [PDF]

Pharmaceuticals (Basel)
Karpova N, Fefilova E, Daks A, Parfenyev S, Nazarov A, Barlev NA, Shuvalov O.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Research on the inhibitory effect of hydrogen gas on ovarian cancer and potential mechanisms. [PDF]

Eur J Med Res
Yin M, Liu M, Zhang C, Peng L, Guo Z, Hao Y, Wang Y, Zhang X, Shi Q, Ren X, Li H, Zhang L.   +11 more
europepmc   +1 more source

Inhibitory Effect of Eucommia Bark on Tumour Formation in a Mouse Model of Two-Stage Skin Carcinogenesis

, 2013
Ken Yasukawa
openalex   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

The inhibitory effect and targets of CRM197 on tumor growth in arsenic-transformed cells and lung cancer cells. [PDF]

Sci Rep
Zhang X, Song S, Tang J, Zhang K, Zhou X, Ma J, Bai X, Shen H, Su D, Wang M.   +9 more
europepmc   +1 more source

The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells

, 2014
Osamu Nakamura, Toshiaki Hitora, Yoshiki Yamagami, Masaki Mori, Hideki Nishimura, RYOSUKE HORIE, Konosuke Yamaguchi, Tetsuji Yamamoto   +7 more
openalex   +2 more sources