Results 71 to 80 of about 1,589,274 (291)

The Role of Magnetic Fields in Setting the Star Formation Rate and the Initial Mass Function

Frontiers in Astronomy and Space Sciences, 2019
Star-forming gas clouds are strongly magnetized, and their ionization fractions are high enough to place them close to the regime of ideal magnetohydrodyamics on all but the smallest size scales.
Mark R. Krumholz, Mark R. Krumholz, Christoph Federrath, Christoph Federrath   +3 more
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Exploring NGC 2345: A Comprehensive Study of a Young Open Cluster through Photometric and Kinematic Analysis

The Astronomical Journal
We conducted a photometric and kinematic analysis of the young open cluster NGC 2345 using CCD UBV data from 2 m Himalayan Chandra Telescope, Gaia Data Release 3, Two Micron All-Sky Survey, and the Photometric All-Sky Survey data sets. We found 1732 most
Kuldeep Belwal, D. Bisht, Mohit Singh Bisht, Geeta Rangwal, Ashish Raj, Arvind K. Dattatrey, R. K. S. Yadav, B. C. Bhatt   +7 more
doaj   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

The Variation in the Galaxy-wide Initial Mass Function for Low-mass Stars: Modeling and Observational Insights

The Astrophysical Journal
The stellar initial mass function (IMF) characterizes the mass distribution of newly formed stars in various cosmic environments, serving as a fundamental assumption in astrophysical research. Recent findings challenge the prevalent notion of a universal
Zhiqiang Yan, Jiadong Li, Pavel Kroupa, Tereza Jerabkova, Eda Gjergo, Zhi-Yu Zhang   +5 more
doaj   +1 more source

The Initial Core Mass Function due to Ambipolar Diffusion in Molecular Clouds [PDF]

, 2009
We show that the ambipolar-diffusion--initiated fragmentation of molecular clouds leads simply and naturally to an initial core mass function (CMF) which is very similar to the initial stellar mass function (IMF) and in excellent agreement with existing observations. This agreement is robust provided that the three (input) free parameters remain within
arxiv   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Simulating Brown Dwarf Observations for Various Mass Functions, Birthrates, and Low-mass Cutoffs

The Astrophysical Journal
After decades of brown dwarf discovery and follow-up, we can now infer the functional form of the mass distribution within 20 pc, which serves as a constraint on star formation theory at the lowest masses.
Yadukrishna Raghu, J. Davy Kirkpatrick, Federico Marocco, Christopher R. Gelino, Daniella C. Bardalez Gagliuffi, Jacqueline K. Faherty, Steven D. Schurr, Adam C. Schneider, Aaron M. Meisner, Marc J. Kuchner, Hunter Brooks, Jake Grigorian, The Backyard Worlds: Planet 9 Collaboration   +12 more
doaj   +1 more source

On the effects of dynamical evolution on the initial mass function of globular clusters [PDF]

, 1997
In this paper we show the results of a large set of N-body simulations modelling the evolution of globular clusters driven by relaxation,stellar evolution,disk shocking and including the effects of the tidal field of the Galaxy. We investigate the evolution of multi-mass models with a power-law initial mass function (IMF) starting with different ...
arxiv   +1 more source