Results 71 to 80 of about 3,434,376 (288)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Why is the Star Formation Rate Proportional to Dense Gas Mass?

The Astrophysical Journal
One of the most profound empirical laws of star formation is the Gao–Solomon relation, a linear correlation between the star formation rate (SFR) and the dense molecular gas mass.
Sihan Jiao, Fengwei Xu, Hauyu Baobab Liu, Yuxin Lin, Jingwen Wu, Zhi-Yu Zhang, Zhiqiang Yan, Di Li, Chao-Wei Tsai, Yongkun Zhang, Linjing Feng, Ke Wang, Zheng Zheng, Fanyi Meng, Hao Ruan, Fangyuan Deng, Keyun Su   +16 more
doaj   +1 more source

Initial Mass Function and Galactic Chemical Evolution Models [PDF]

, 2005
4 pages, 2 figures, uses kapproc.cls. Contributed talk presented at the conference on "IMF@50: The Stellar Initial Mass Function Fifty Years Later" held at Abbazia di Spineto, Siena, Italy, May 2004. To be published by Kluwer Academic Publishers, ed. E. Corbelli, F.
Romano, Donatella, Chiappini, Cristina, Matteucci, Francesca, Tosi, Monica   +3 more
openaire   +2 more sources

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Comparison of physical characteristics of mass and luminosity function of disk systems in barred and unbarred spiral galaxies

مجلة بغداد للعلوم
Among the most important ways to investigate galaxies' distribution over cosmic time is the luminosity function LF in terms of baryonic disc mass ψS(Mb), magnitude  .
Al Najm M.N., Y. E. Rashed , H. H. AL-Dahlaki   +2 more
doaj   +1 more source

Constraints on primordial black holes from Galactic gamma-ray background

, 2016
The fraction of the Universe going into primordial black holes (PBHs) with initial mass M_* \approx 5 \times 10^{14} g, such that they are evaporating at the present epoch, is strongly constrained by observations of both the extragalactic and Galactic ...
Carr, B. J., Kohri, Kazunori, Sendouda, Yuuiti, Yokoyama, Jun'ichi   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Monte-Carlo experiments on star-cluster induced integrated-galaxy IMF variations

, 2004
As most if not all stars are born in stellar clusters the shape of the mass function of the field stars is not only determined by the initial mass function of stars (IMF) but also by the cluster mass function (CMF).
Kroupa, Pavel, Weidner, Carsten
core   +1 more source

The Stellar Initial Mass Function

, 1999
The current status of both the observational evidence and the theory of the stellar initial mass function (IMF) is reviewed, with particular attention to the two basic, apparently universal features shown by all observations of nearby stellar systems: (1) a characteristic stellar mass of the order of one solar mass, and (2) a power-law decline of the ...
openaire   +2 more sources