Results 121 to 130 of about 143,162 (326)

A Robust Measure of Tidal Circularization in Coeval Binary Populations: The solar-type spectroscopic Binary Population in The Open Cluster M35

open access: yes, 2004
We present a new homogeneous sample of 32 spectroscopic binary orbits in the young (~ 150 Myr) main-sequence open cluster M35. The distribution of orbital eccentricity vs.
Claret A.   +23 more
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

INPOP08, a 4-D planetary ephemeris: From asteroid and time-scale computations to ESA Mars Express and Venus Express contributions

open access: yes, 2009
The latest version of the planetary ephemerides developed at the Paris Observatory and at the Besancon Observatory is presented here. INPOP08 is a 4-dimension ephemeris since it provides to users positions and velocities of planets and the relation ...
A. Fienga   +24 more
core   +4 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A Novel Algorithm for Precise Orbit Determination Using a Single Satellite Laser Ranging System Within a Single Arc for Space Surveillance and Tracking

open access: yesAerospace
A satellite laser ranging (SLR) system uses lasers to measure the range from ground stations to space objects with millimeter-level precision. Recent advances in SLR systems have increased their use in space surveillance and tracking (SST).
Dong-Gu Kim, Sang-Young Park, Eunji Lee
doaj   +1 more source

Perturbations in the optimized boundary value initial orbit determination approach

open access: green, 2020
Harleen Kaur Mann   +2 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

An open Monte Carlo based implementation of Gauss's method for initial orbit determination

open access: yesTecnociencia
Hundreds or thousands of Near-Earth Asteroids (NEAs) are discovered every year, so being able to determine their orbits to follow them successfully in the future is essential to warn of the danger they could present. Numerous methods have been developed
José B. Batista-Mendoza   +4 more
doaj   +1 more source

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