Results 41 to 50 of about 8,644,148 (262)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A Bayesian optimized framework for successful application of unscented Kalman filter in parameter identification of MDOF structures

Journal of Low Frequency Noise, Vibration and Active Control, 2021
The success of the unscented Kalman filter can be jeopardized if the required initial parameters are not identified carefully. These parameters include the initial guesses and the levels of uncertainty in the target parameters and the process and ...
Mohamadreza Sheibani, Ge Ou
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Evolution of Cos–Gaussian Beams in the Periodic Potential Optical Lattice

Crystals, 2022
The evolution of Cos−Gaussian beams in periodic potential optical lattices is theoretically and numerically investigated. By theoretical analysis, a breathing soliton solution of the Gross–Pitaevskii equation with periodic potential is obtained, and the ...
Bing Wen, Yangbao Deng, Jiamou Wei, Depeng Chen, Xiaoling Leng   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Analyzing, investigating and calculating the optimum mode of the parameters affecting the record of the javelin throw including the initial velocity, initial angle, and initial height of throw

Turkish Journal of Kinesiology, 2019
The javelin throw is a track and field event, which is of very great antiquity. The most important goal in the javelin throw is the throwing record.
Yousef Jalalabadi, Samaneh Mohammadi, Fateme Nikkhoo Amiri   +2 more
doaj   +1 more source

Initial and Delayed Metabolic Activity of Palatine Tonsils Measured with the PET/CT-Dedicated Parameters

Diagnostics, 2020
One of the most critical elements in the palatine tonsils (PT) patients’ management is to distinguish chronic tonsillitis and malignant tumor. The single-time-point (STP) 2-deoxy-2-[18 F]fluoro-D-glucose positron emission tomography/computed tomography ...
Agata Pietrzak, Andrzej Marszalek, Malgorzata Paterska, Pawel Golusinski, Julitta Narozna, Witold Cholewinski   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Initial Clinical Presentation and Laboratory Parameters of Indoor Hiv-Positive Patients

Pakistan Armed Forces Medical Journal
Objective: To determine the pattern of the clinical presentation and laboratory parameters and factors associated with low CD-4 count among the patients hospitalized for initial presentation of human immune deficiency virus (HIV) in Pak Emirates ...
Aimen Sabir, Shazia Nisar, Khalid Mahmood Raja, Ayesha Anwer, Marriam Hussain Awan, Maria Tariq   +5 more
doaj   +1 more source