Results 61 to 70 of about 1,839,289 (262)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Preliminary Investigation into Tree Dryness in Hevea brasiliensis (Wild. Ex Adr. De Juss) Muell. Arg. by Path Analysis of Tree Dryness and Latex Parameters [PDF]

open access: yesTropicultura, 2001
The correlative path analysis between tree dryness and four latex parameters was studied in eleven clones of Hevea brasiliensis. The latex parameters used for evaluation were initial volume, initial flow rate, final volume and plugging index with tree ...
Omokhafe, KO.
doaj  

Global optimization of the electron acceleration by a Gaussian beam

open access: yesResults in Physics, 2017
For vacuum electron acceleration by a Gaussian beam, the energy gain of the electron is sensitively influenced by the initial parameters of the electron and the laser beam.
Jian Xu   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Technological evaluation of grain in collection samples of naked oat in the conditions of Northern forest-steppe of the Tyumen region

open access: yesАграрная наука Евро-Северо-Востока, 2017
Oats - is a crop of universal use both for feed and food purposes. Naked varieties are of particular interest in this regard. At grain’s evaluating for the processing industry, it is necessary to define such technological grain properties as test weight ...
Y. S. Ivanova, M. N. Fomina
doaj  

Rational Choice of the Investment Project Using Interval Estimates of the Initial Parameters [PDF]

open access: yesProblemi Ekonomiki, 2016
The article is dedicated to the development of instruments to support decision-making on the problem of choosing the best investment project in a situation when initial quantitative parameters of the considered investment alternatives are described by
Kotsyuba Oleksiy S.
doaj  

Parameter initialization for warm-starting QAOA

open access: yes, 2022
Der Quantum Approximate Optimization Algorithm (QAOA) ist ein vielversprechender Kandidat für Quantenüberlegenheit auf Near-Term-Hardware. Warm-started QAOA (WS-QAOA) ist eine verbesserte Version von QAOA. Diese nutzt für das vorliegende Problem eine vorberechnete approximative Lösung, welche effizient auf klassischer Hardware bestimmt wird.
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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