Results 31 to 40 of about 3,499,923 (363)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Building Professional Identity during Pre-Service Teacher Education
Center for Educational Policy Studies Journal, 2021 This article explores how university learning and the period of school placement can contribute to identity development understood as a dynamic and evolving process.
Gemma Torres-Cladera +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Terra de Pretos, 2020 This article is an experience report on the use of literacy games as a didactic strategy for initial learning of reading and writing, carried out by a group of scholarship students from the Institutional Scholarship Program for Teaching Initiation (Pibid/
Daniela Montuani +2 more
doaj
Ecomatemático, 2016 Implementation of technology in teaching-learning mathematics requires a change in teaching practice. This change can be promoted from the initial training of mathematics teachers.
Judith Hernández-Sánchez +2 more
doaj +1 more source
Le patient : le tiers impensé dans l’apprentissage du raisonnement clinique
Éducation et Socialisation, 2021 As part of the "reengineering" of initial studies of physiotherapy, it is sought to understand the situation of transmission-learning of the clinical reasoning of a student and his tutor in an internship situation, during the first patient encounter. The
Delphine Guyet, Jean-Luc Rinaudo
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source