Results 61 to 70 of about 3,499,923 (363)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Study on the digital competencies of prospective pre-school and primary school teachers and the influence of gender and academic performance

Journal of Technology and Science Education
ICT can be a powerful tool for learning, but it is crucial that teachers know how to use it effectively. Digital competence enables teachers to tailor learning to the individual needs of students, making it more engaging and motivating, while creating ...
Enrique Alastor, Francisco David Guillén-Gámez, Julio Ruiz-Palmero   +2 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Les langues étrangères : clé de réussite pour une meilleure employabilité [PDF]

Revue Roumaine d’Etudes Francophones, 2020
The present article aims to present the project “Bâtir mon projet professionnel pour une meilleure employabilité (BPME - Building my Professional Project for Better Employability)”.
Cristiana-Nicola TEODORESCU, Daniela DINCĂ   +1 more
doaj  

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Perceptions of Students of Education Sciences on Research Ethics and (Re)Formation of the University Curriculum

Education Sciences
The study investigates perceptions of students of education sciences in Romania concerning issues related to research ethics, starting from recent opinions that consider the lack of adequate training in this field as a threat to higher education.
Dorin Opriş
doaj   +1 more source

Links between ICT advanced skills teachers and initial teacher training [PDF]

, 2011
This report and guidance materials were compiled for the Training and Development Agency for Schools (TDA)Research undertaken at one higher education institution located in West London, UK sought to explore links between ICT Avanced Skills Teachers (AST)
Audain, J, Zwozdiak-Myers, P
core  

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Analysis of Teacher Self-Efficacy and Its Impact on Sustainable Well-Being at Work

Behavioral Sciences
This study evaluates teacher self-efficacy perceptions among students in the Master’s Degree in Secondary Education and Baccalaureate, Vocational Training, and Language Teaching (MDSE), as well as the variables influencing these perceptions and their ...
Mercedes Arias-Pastor, Steven Van Vaerenbergh, Jerónimo J. González-Bernal, Josefa González-Santos   +3 more
doaj   +1 more source