Results 141 to 150 of about 1,329,071 (310)
Initiative Inklusion Österreich: Manifest zur Umsetzung der UN-Konvention
Die Initiative Inklusion Österreich hat ein Manifest zur Umsetzung der UN-Konvention erarbeitet. Die Initiative ersucht um aktive Unterstützung des Forderungspapiers. Daher liegt auch eine Unterschriftenliste bei.
Initiative Inklusion Österreich, .
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
İşgörenlerin Kendilik Algılarının Bireysel Özellikler Bakımından Değerlendirilmesi
Kendilik algısıbireyin özel ve işyaşamıyla ilgili olduğu kadar, sosyal yaşamıyla da ilgilidir. Kendilik algısıyüksek şahısların öz saygıları, öz güvenleri ve ben idrakleri güçlüdür. Kişiler arasıilişki ve etkileşim kurmada başarılıdırlar.
Hasan Tutar +2 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Peckham Outer-Space Initiative
"In Ships Not Shelters, the Peckham Outer-Space Initiative (POI) has produced a publication creatively renouncing the stasis inherent in the idea of a shelter, and instead embracing the ship as a vehicle (physically, mentally) for some diagonal forward ...
Feo, Roberto +3 more
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

