Results 111 to 120 of about 35,938 (311)

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source

Highly-stable, injectable, conductive hydrogel for chronic neuromodulation

Nature Communications
Electroceuticals, through the selective modulation of peripheral nerves near target organs, are promising for treating refractory diseases. However, the small sizes and the delicate nature of these nerves present challenges in simplifying the fixation ...
Ming Yang, Lufang Wang, Wenliang Liu, Wenlong Li, Yewei Huang, Qiaofeng Jin, Li Zhang, Yuanwen Jiang, Zhiqiang Luo   +8 more
doaj   +1 more source

Combined release of platelet-rich plasma and 3D-mesenchymal stem cell encapsulation in alginate hydrogels modified by the presence of silica [PDF]

, 2011
We report the modified release of platelet-rich plasma from alginate platelet-rich plasma hydrogels altered by the presence of silica. These PRP–alginate–silica compositions can be used as injectable carriers for viable mesenchymal stem ...
Alini, M, Eglin, D, Gimeno-Fabra, M, Peroglio, M, Perry, CC   +4 more
core   +1 more source

All‐Aqueous Pullulan Fibers Enabling Visible‐to‐Near‐Infrared Waveguiding with Mechanical and Thermal Resilience

Advanced Functional Materials, EarlyView.
Pullulan, a biomass‐derived polysaccharide, is transformed into transparent optical fibers using a solvent‐free borax hydrogel‐spinning method. The fibers outperform PMMA with ≈200 MPa tensile strength and 200 °C stability, while uniquely guiding visible‐to‐NIR light and enabling additive‐free humidity sensing.
Yuya Fukata, Aayush Kumar Jaiswal, Ari Hokkanen, Hannes Orelma, Tadahisa Iwata   +4 more
wiley   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science
Myocardial ischemia‐reperfusion injury (MIRI) is a leading cause of complications and high mortality associated with acute myocardial infarction. Injectable hydrogel emerges as a promising biomaterial for myocardial repair due to their ability to mimic ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
doaj   +1 more source

Biological evaluation of alginate-based hydrogels, with antimicrobial features by Ce(III) incorporation, as vehicles for a bone substitute [PDF]

, 2013
In this work three different hydrogels were developed to associate, as vehicles, with the synthetic bone substitute GR-HA. One based on an alginate matrix (Alg); a second on a mixture of alginate and chitosan (Alg/Ch); and a third on alginate and ...
A Chen, A. C. Maurício, AK Gaharwar, AR Vaccaro, AY Peleg, BD Ulery, BV Slaughter, C. M. Botelho, D Campoccia, D Campoccia, D Couto, D Yang, D. S. Morais, DS Morais, E Martínez-Sanz, E Martínez-Sanz, E West, GA Carlson, GD Prestwich, H Liu, H Zhang, I Aranaz, I Nagaoka, I. Amorim, IA Gwynn, J Kim, J Patterson, J. D. Santos, JF Mano, JP Garner, K Anselme, K Diba, KJ Zaleski, L Cobrado, L Wang, LS Nair, M Amaral, M Gutierres, M. A. Lopes, M. A. Rodrigues, M. J. Coelho, M. P. Ferraz, MA Jakupec, MA Lopes, MA Lopes, MB Brown, MPG Bostrom, P Sriamornsak, P Wutticharoenmongkol, PV Giannoudis, R Lima, R Palffy, R. Gomes, S Gariboldi, S Larsson, S Takahashi, SM Oliveira, T Andersen, TW Chunga, U Hempel   +59 more
core   +1 more source

Injectable cell-laden silk acid hydrogel

Chemical Communications
A physically crosslinked protein-based hydrogel was developed based on silk acid. It can be produced under physiological conditions with a modulus close to the extracellular matrix, supporting 3D cell culture and cell-laden injection.
Ziyang Sun, Haoran Liu, Dandan Dai, Hao Lyu, Ruochuan Huang, Wenzhao Wang, Chengchen Guo   +6 more
openaire   +2 more sources

Conductive Bonding and System Architectures for High‐Performance Flexible Electronics

Advanced Functional Materials, EarlyView.
This review outlines bonding technologies and structural design strategies that support high‐performance flexible and stretchable electronics. Bonding approaches such as surface‐activated bonding and anisotropic conductive films, together with system‐level architectures including buffer layers and island‐bridge structures, possess distinct mechanical ...
Kazuma Nakajima, Kenjiro Fukuda
wiley   +1 more source