Results 11 to 20 of about 35,938 (311)
Injectable Hydrogels for Localized Cancer Therapy [PDF]
Frontiers in Chemistry, 2019 Traditional intravenous chemotherapy is relative to many systemic side effects, including myelosuppression, liver or kidney dysfunction, and neurotoxicity.
Dao-yang Fan, Yun Tian, Zhong-jun Liu
doaj +3 more sources
Injectable Biodegradable Hydrogels [PDF]
Macromolecular Bioscience, 2010 AbstractInjectable biodegradable copolymer hydrogels, which exhibit a sol–gel phase transition in response to external stimuli, such as temperature changes or both pH and temperature (pH/temperature) alterations, have found a number of uses in biomedical and pharmaceutical applications, such as drug delivery, cell growth, and tissue engineering.
Minh Khanh, Nguyen, Doo Sung, Lee
openaire +2 more sources
Injectable Hydrogels: From Laboratory to Industrialization [PDF]
Polymers, 2021 The transfer of some innovative technologies from the laboratory to industrial scale is many times not taken into account in the design and development of some functional materials such as hydrogels to be applied in the biomedical field. There is a lack of knowledge in the scientific field where many aspects of scaling to an industrial process are ...
Alonso, Jose Maria +3 more
openaire +2 more sources
Journal of Polymer Science Part B: Polymer Physics, 2012 AbstractHydrogels are promising for a variety of medical applications due to their high water content and mechanical similarity to natural tissues. When made injectable, hydrogels can reduce the invasiveness of application, which in turn reduces surgical and recovery costs.
Derek J. Overstreet +3 more
openaire +1 more source
Injectable therapeutic organoids using sacrificial hydrogels [PDF]
iScience, 2020 AbstractOrganoids, by promoting self-organization of cells into native-like structures, are becoming widespread in drug-screening technologies, but have so far been used sparingly for cell therapy as current approaches for producing self-organized cell clusters lack scalability or reproducibility in size and cellular organization. We introduce a method
Ninna S. Rossen +16 more
openaire +3 more sources
Click‐Crosslinked Injectable Gelatin Hydrogels [PDF]
Advanced Healthcare Materials, 2016 Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for high viability of encapsulated cells ...
Rabbind Singh, Amrathlal +15 more
openaire +3 more sources
Injectable hydrogels for ophthalmic applications [PDF]
Journal of Controlled Release, 2017 The demand for effective eye therapies is driving the development of injectable hydrogels as new medical devices for controlled delivery and filling purposes. This article introduces the properties of injectable hydrogels and summarizes their versatile application in the treatment of ophthalmic diseases, including age-related macular degeneration ...
Kai Wang, Zongchao Han
openaire +2 more sources
Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. [PDF]
, 2018 Injectable hydrogels with tunable physiochemical and biological properties are potential tools for improving neural stem/progenitor cell (NSPC) transplantation to treat central nervous system (CNS) injury and disease.
Czechanski, A +6 more
core +1 more source
Coassembly Generates Peptide Hydrogel with Wound Dressing Material Properties [PDF]
, 2020 Multicomponent self-assembly of peptides is a powerful strategy to fabricate novel functional materials with synergetic properties that can be used for several nanobiotechnological applications.
Berger, Allison A. +5 more
core +1 more source
Tissue compatibility of poly(hydroxypropylglutamate)-prazosin conjugates [PDF]
, 1992 Biocompatibility of an injectable biodegradable drug delivery system for prazosin was investigated in Sprague-Dawley rats by histological studies after subcutaneous injection ofpoly(hydroxypropyl glutamate)-prazosin (PHPG-prazosin) conjugate particles ...
Anderson, James M. +4 more
core +2 more sources