Results 271 to 280 of about 35,938 (311)

Injectable hydrogels for personalized cancer immunotherapies

Acta Biomaterialia, 2023
The field of cancer immunotherapy has shown significant growth, and researchers are now focusing on effective strategies to enhance and prolong local immunomodulation. Injectable hydrogels (IHs) have emerged as versatile platforms for encapsulating and controlling the release of small molecules and cells, drawing significant attention for their ...
Neda Mohaghegh, Amir Ahari, Fatemeh Zehtabi, Claire Buttles, Saya Davani, Hanna Hoang, Kaylee Tseng, Benjamin Zamanian, Safoora Khosravi, Ariella Daniali, Negar Hosseinzadeh Kouchehbaghi, Isabel Thomas, Hamed Serati Nouri, Danial Khorsandi, Reza Abbasgholizadeh, Mohsen Akbari, Rameshwar Patil, Heemin Kang, Vadim Jucaud, Ali Khademhosseini, Alireza Hassani Najafabadi   +20 more
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Mechanically Reinforced Injectable Hydrogels

ACS Applied Polymer Materials, 2019
Injectable hydrogels have garnered significant research attention in biomedical applications due to their ability to be delivered to a target site via a minimally invasive route.
Kevin J. De France, Emily D. Cranston, Todd Hoare   +2 more
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Injectable biodegradable hydrogels: progress and challenges

Journal of Materials Chemistry B, 2013
Over the past decades, injectable hydrogels have emerged as promising biomaterials because of their biocompatibility, excellent permeability, minimal invasion, and easy integration into surgical procedures. These systems provide an effective and convenient way to administer a wide variety of bioactive agents such as proteins, genes, and even living ...
Ki Hyun, Bae, Li-Shan, Wang, Motoichi, Kurisawa   +2 more
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Injectable hydrogels as unique biomedical materials

Chemical Society Reviews, 2008
A concentrated fish soup could be gelled in the winter and re-solled upon heating. In contrast, some synthetic copolymers exhibit an inverse sol-gel transition with spontaneous physical gelation upon heating instead of cooling. If the transition in water takes place below the body temperature and the chemicals are biocompatible and biodegradable, such ...
Lin, Yu, Jiandong, Ding
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Rapid Photocrosslinkable Thermoresponsive Injectable Polyphosphazene Hydrogels

Macromolecular Rapid Communications, 2010
AbstractRapidly photocrosslinkable and thermosensitive polyphosphazene polymers have been prepared to overcome the limitations associated with long UV exposure. Short UV exposure on the thermosensitive gels under mild conditions leads to quick photocrosslinking of the acrylate groups in the polymer network, and results in a dual crosslinked network ...
Thrimoorthy, Potta, Changju, Chun, Soo-Chang, Song   +2 more
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Injectable hydrogels for delivering biotherapeutic molecules

International Journal of Biological Macromolecules, 2018
To date, numerous delivery systems based on either organic or inorganic material have been developed to achieve efficient and sustained delivery of therapeutics. Hydrogels, which are three dimensional networks of crosslinked hydrophilic polymers, have a significant role in solving the clinical and pharmacological limitations of present systems because ...
Ansuja Pulickal, Mathew, Saji, Uthaman, Ki-Hyun, Cho, Chong-Su, Cho, In-Kyu, Park   +4 more
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Injectable Hydrogels from Segmented PEG-Bisurea Copolymers

Biomacromolecules, 2012
We describe the preparation of an injectable, biocompatible, and elastic segmented copolymer hydrogel for biomedical applications, with segmented hydrophobic bisurea hard segments and hydrophilic PEG segments. The segmented copolymers were obtained by the step growth polymerization of amino-terminated PEG and aliphatic diisocyanate.
Pawar, G.M., Koenigs, M.M.E, Fahimi, Z., Cox, M.A.J., Voets, I.K., Wyss, H.M., Sijbesma, R.P.   +6 more
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Injectable Intraocular Lens Materials Based upon Hydrogels

Biomacromolecules, 2001
The possibilities to develop an injectable hydrogel lens were investigated. Aqueous solutions of reactive polymers in combination with a water-soluble blue light photoinitiator were transformed into hydrogels by irradiation with blue light. Poly(ethylene glycol) diacrylates (PEGDA) with low molecular weights and an acrylate modified copolymer of N ...
de Groot, JH, van Beijma, FJ, Haitjema, HJ, Dillingham, KA, Hodd, KA, Koopmans, SA, Norrby, S   +6 more
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Injectable intraocular lens using hydrogels

Journal of Drug Delivery Science and Technology, 2007
Presbyopia is an age-related condition that begins to develop in humans around the age of forty, resulting in anatomical and physiological changes in the choroids, ciliary body, vitreous, lens capsule, and lens fibers. A suitable biomaterial is needed for the implantation of intraocular lenses (IOL) that could be used to treat the symptoms of ...
M.K. Yoo, Y.J. Choi, J.H. Lee, W.R. Wee, C.S. Cho   +4 more
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Therapeutic Injectable Iron-Chelating Hydrogels

2022
VCU Theses and ...
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