Results 31 to 40 of about 35,938 (311)

Chemical signal regulated injectable coacervate hydrogels

Chemical Science, 2023
Incorporation of reversible Michael addition controlled coacervate crosslinks in a polymer hydrogel led to injectable gels that are responsive to nucleophilic chemical signals, enabling accelerated degradation in culture media after injection.
Bohang Wu, Reece W. Lewis, Guotai Li, Yifan Gao, Bowen Fan, Benjamin Klemm, Jianan Huang, Junyou Wang, Martien A. Cohen Stuart, Rienk Eelkema   +9 more
openaire   +4 more sources

Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats

Stem Cells International, 2019
Stem cell-based tissue engineering in treating intervertebral disc (IVD) degeneration is promising. An appropriate cell scaffold can maintain the viability and function of transplanted cells.
Feng Wang, Li-ping Nan, Shi-feng Zhou, Yang Liu, Ze-yu Wang, Jing-cheng Wang, Xin-min Feng, Liang Zhang   +7 more
doaj   +1 more source

Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]

, 2013
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa, Gopalan, Began, Hauser, Charlotte A. E., Joshi, Mangesh, Lakshmanan, Anupama, Lam, Dang Hoang, Mishra, Archana, Reithofer, Michael R., Wang, Shu   +8 more
core   +1 more source

Synergistic osteogenic and angiogenic effects of KP and QK peptides incorporated with an injectable and self-healing hydrogel for efficient bone regeneration

Bioactive Materials, 2022
Irregular defects generated by trauma or surgery in orthopaedics practice were usually difficult to be fitted by the preformed traditional bone graft substitute.
Runze Li, Chen Zhou, Jun Chen, Haotian Luo, Ruoyu Li, Danying Chen, Xuenong Zou, Weicai Wang   +7 more
doaj   +1 more source

Pluronic F-127 hydrogel as a promising scaffold for encapsulation of dental-derived mesenchymal stem cells. [PDF]

, 2015
Dental-derived mesenchymal stem cells (MSCs) provide an advantageous therapeutic option for tissue engineering due to their high accessibility and bioavailability.
Ansari, Sahar, Chen, Chider, Diniz, Ivana MA, Marques, Márcia M, Moshaverinia, Alireza, Shi, Songtao, Xu, Xingtian, Zadeh, Homayoun H   +7 more
core   +1 more source

Heparin modified polyethylene glycol microparticle aggregates for focal cancer chemotherapy [PDF]

, 2016
Focal cancer therapy can improve clinical outcomes. Here, we evaluated injectable heparin-containing hydrogel material loaded with doxorubicin as a focal breast cancer therapy.
Freudenberg, Uwe, Kaplan, David L., Seib, F. Philipp, Tsurkan, Mikhail, Werner, Carsten   +4 more
core   +2 more sources

Gt-F Hydrogel: Photodynamic And Regenerative Multifunctional Adhesive

International Dental Journal
Aim or purpose: This study introduces a novel injectable multifunctional hydrogel adhesive with light-controlled antibacterial properties and cell growth promotion, addressing challenges in peri-implantitis management.
Jiarun Li
doaj   +1 more source

Injectable and biodegradable double-network nanocomposite hydrogel with regulable sol-gel transition process and mechanical properties

Polymer Testing, 2022
Alginate hydrogels have the most extensively explored injection system among natural molecular. The injectable alginate hydrogel has special physical and biological properties without toxicity, therefore, it has been served as minimally invasive ...
Ziyuan Fang, Kun Qiao, Yansen Wang, Yudong Zheng, Wei He, Yajie Xie, Huiyi Yang   +6 more
doaj   +1 more source

Evidence for mechanisms underlying the functional benefits of a myocardial matrix hydrogel for post-MI treatment [PDF]

, 2016
Background There is increasing need for better therapies to prevent the development of heart failure after myocardial infarction (MI). An injectable hydrogel derived from decellularized porcine ventricular myocardium has been shown to halt the post ...
Braden, Rebecca L., Christman, Karen L., Demaria, Anthony N., Gaetani, Roberto, Garcia, Julian J., Huang, Diane, Luo, Colin G., Omens, Jeffrey H., Wassenaar, Jean W.   +8 more
core   +1 more source

Injectable Hydrogels for Cardiac Tissue Engineering [PDF]

Macromolecular Bioscience, 2018
AbstractIn light of the limited efficacy of current treatments for cardiac regeneration, tissue engineering approaches have been explored for their potential to provide mechanical support to injured cardiac tissues, deliver cardio‐protective molecules, and improve cell‐based therapeutic techniques.
Brisa Peña, Melissa Laughter, Susan Jett, Teisha J. Rowland, Matthew R. G. Taylor, Luisa Mestroni, Daewon Park   +6 more
openaire   +2 more sources