Results 51 to 60 of about 35,938 (311)

Development of an injectable PHBV microparticles-GG hydrogel hybrid system for regenerative medicine [PDF]

, 2015
Uncontrollable displacements that greatly affect the concentration of active agents at the target tissues are among a major limitation of the use of microparticulate drug delivery systems (DDS). Under this context a biphasic injectable DDS combining poly(
Amaral, Maria H., Correlo, V. M., Marques, A. P., Pacheco, Daniela P., Reis, R. L.   +4 more
core   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Self-assembled injectable Icariin@ Ti3C2Tx/doxorubicin hydrogel preserving osteogenesis while synergizing photodynamic and chemodynamic therapy for osteosarcoma

Journal of Materials Science: Materials in Medicine
Local therapy involving injectable hydrogel systems loaded with doxorubicin (DOX) has garnered significant attention in the realm of osteosarcoma (OS) research.
Jiahao Fu, Hao Chen, Yiqiao Zhao, Hongzhong Xi, Yixuan Huang, Chenglin Liu, Yaokun Wu, Wei Song, Xin Liu, Bin Du, Guangquan Sun   +10 more
doaj   +1 more source

A graphene oxide/silica@sodium alginate injectable hydrogel scaffold for potential application in bone tissue engineering

Next Materials
With the rising occurrence of bone defects and the advancement of bone tissue engineering, developing suitable bone alternative scaffolds presents a major challenge.
Runjia Wang, Baojin Ma
doaj   +1 more source

Injectable and Antioxidative HT/QGA Hydrogel for Potential Application in Wound Healing

Gels, 2021
Hydrogels have gained a niche in the market as wound dressings due to their high water content and plasticity. However, traditional hydrogel wound dressings are difficult to fully adapt to irregular-shaped wound areas.
Yikun Ren, Dan Zhang, Yuanmeng He, Rong Chang, Shen Guo, Shanshan Ma, Minghao Yao, Fangxia Guan   +7 more
doaj   +1 more source

Foreign body responses in central nervous system mimic natural wound responses and alter biomaterial functions [PDF]

, 2019
Biomaterials hold promise for diverse therapeutic applications in the central nervous system (CNS). Little is known about molecular factors that determine CNS foreign body responses (FBRs) in vivo , or about how such responses influence biomaterial ...
Ao, Yan, Deming, Timothy, Kim, Jae, O’Shea, Timothy, Sofroniew, Michael, Wollenberg, Alexander   +5 more
core   +1 more source

Biocompatibility of injectable resilin‐based hydrogels [PDF]

Journal of Biomedical Materials Research Part A, 2018
AbstractVocal folds are connective tissues housed in the larynx, which can be subjected to various injuries and traumatic stimuli that lead to aberrant tissue structural alterations and fibrotic‐induced biomechanical stiffening observed in patients with voice disorders.
Linqing Li, Jeanna M. Stiadle, Elizabeth E. Levendoski, Hang K. Lau, Susan L. Thibeault, Kristi L. Kiick   +5 more
openaire   +2 more sources

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

A Biocompatible, Stimuli-Responsive, and Injectable Hydrogel with Triple Dynamic Bonds

Molecules, 2020
Injectable hydrogels have attracted growing interests as promising biomaterials for clinical applications, due to their minimum invasive implanting approach and easy-handling performance. Nevertheless, natural biomaterials-based injectable hydrogels with
Yujie Chen, Runjing Zhang, Baiqin Zheng, Chao Cai, Zhen Chen, Hua Li, Hezhou Liu   +6 more
doaj   +1 more source

Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury

Materials Today Bio, 2022
Injectable Hydrogels with adhesive, antioxidant and hemostatic properties are highly desired for promoting skin injury repair. In this study, we prepared a multi-functional carboxymethyl chitosan/hyaluronic acid-dopamine (CMC/HA-DA) hydrogel, which can ...
Longlong Cui, Jiankang Li, Shuaimeng Guan, Kaixiang Zhang, Kun Zhang, Jingan Li   +5 more
doaj   +1 more source