Results 41 to 50 of about 1,755,239 (267)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Modeling fluid injection into a porous spherical composite with anisotropy [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика
Porous spherical composites are widely found both in natural objects and in technical applications. To describe the mechanical behavior of such structures, it is necessary to take into account the interaction of solid and fluid phases, since the fluid ...
Kucherenko, Denis V.
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Evaluation of postoperative complications of hypospadias using high-frequency ultrasound imaging

BMC Urology
Purpose Various complications following hypospadias surgery present distinct manifestations when examined with ultrasound. Utilizing high-frequency ultrasound, clinicians can promptly identify these complications and initiate appropriate treatment.
Jun Zhuang, Xueshang Su, Ying Jia, Qiaoyuan Zheng, Qingqian Wei, Ziming Zhang, Jintian Hu, Li Yuan, Hongli Chai   +8 more
doaj   +1 more source

Factors Influencing Litigation Compensation in Plastic Surgery: A Retrospective Analysis in China

Plastic and Reconstructive Surgery, Global Open
Background:. Doctor–patient disputes have become a prominent problem in contemporary society. The analysis and discussion of the factors leading to litigation compensation are essential to prevent and resolve doctor–patient conflicts, reduce litigation ...
Xueshang Su, MD, Yutong Liang, MD, Jun Zhuang, MD, Qingqian Wei, MD, Ziming Zhang, MD, Xue Ouyang, MD, Haixia Jiang, MD, Na Cai, MD, Jintian Hu, MD, Bo Ding, MD   +9 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Injective and non-injective realizations with symmetry

Contributions to Discrete Mathematics, 2010
In this paper, we introduce a natural classification of bar and joint frameworks that possess symmetry. This classification establishes the mathematical foundation for extending a variety of results in rigidity, as well as infinitesimal or static rigidity, to frameworks that are realized with certain symmetries and whose joints may or may not be ...
openaire   +2 more sources

SUBCONJUNCTIVAL INJECTIONS. [PDF]

JAMA: The Journal of the American Medical Association, 1896
n ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

APPLICATION OF A NEW PROTECTIVE MATERIAL TO IMPROVE THE DURABILITY OF ENGINEERING COMMUNICATIONS AS A METHOD OF ENSURING GEOECOLOGICAL SAFETY OF THE URBAN ENVIRONMENT

Современная наука и инновации, 2022
The article is devoted to the problem of providing geoecological safety of the urban environment by creating a reliable protection of underground engineering communications.
Olga Borisovna Lyapidevskaya, Andrey Konstantinovich Sherstnev   +1 more
doaj