Results 111 to 120 of about 724,201 (286)

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi   +2 more
wiley   +1 more source

Numerical Simulation of Microcellular Injection Molding: A Case Study

open access: yesAnnals of "Dunarea de Jos" University of Galati, Fascicle XII, Welding Equipment and Technology
The microcellular injection molding, often referred to as MuCell®, is an innovative polymer processing technique that utilizes supercritical inert gases, such as CO2 or N2, to manufacture lightweight plastic products.
A. Chaabene, A. Ben Khalifa, S. Chatti
doaj   +1 more source

Advanced injection molding technologies /

open access: yes
"This book covers the most recent and important developments in advanced injection molding technologies, such as intelligent process control; technology innovations and computer simulation for emerging special injection molding processes like ...
Turng, Lih-Sheng,editor.   +1 more
core  

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans   +7 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

A learning-based model predictive control scheme for injection speed tracking in injection molding process

open access: yesComplex & Intelligent Systems
Injection molding is a pivotal industrial process renowned for its high production speed, efficiency, and automation. Controlling the motion speed of injection molding machines is a crucial factor that influences production processes, directly affecting ...
Zhigang Ren   +3 more
doaj   +1 more source

Influence of Mold Design and Molding Conditions on the Optical Properties of Contact Lenses

open access: yesSensors
Injection molding is essential for mass-producing soft contact lenses, yet molding-induced deformation remains a decisive factor for optical quality. This study systematically evaluated the impact of resin mold design factors (optical zone (OZ) radius of
Kazumasa Tatsumi   +6 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park   +5 more
wiley   +1 more source

Ultrafast Vertical Organic Electrochemical Transistors With Ion‐Permeable Conductive Polymer Top Electrodes

open access: yesAdvanced Materials, EarlyView.
Vertical organic electrochemical transistors (vOECTs) are limited in speed by ion‐impermeable metal electrodes that slow ion injection. Using ion‐permeable PBFDO top electrodes allows direct vertical ion injection into BBL channels, achieving high current densities (>400 A cm−2), large on/off ratios (>106), and ultrafast switching in 28 µs. This sets a
Han‐Yan Wu   +14 more
wiley   +1 more source

Comparison of the Molding Parameters Effects on Metal Injection Molded Specimens in the Real Experimental and Simulation Environments

open access: yesCommunications
This article presents a technology that is not widely known. Previous research has investigated the effect of metal injection molding parameters on product shrinkage.
György Ledniczky, Zoltán Weltsch
doaj   +1 more source

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